This is biotin-labeled beta-amyloid 3-42. Beta-amyloid is implicated in the pathogenesis of neurodegenerative diseases such as Alzheimer’s and familial Danish dementia. N-terminal pyroglutamate reduces susceptibility to aminopeptidase degradation and may also play an important role in biological function.
Pyr - Phe - Arg - His - Asp - Ser - Gly - Tyr - Glu - Val - His - His - Gln - Lys - Leu - Val - Phe - Phe - Ala - Glu - Asp - Val - Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met - Val - Gly - Gly - Val - Val - Ile - Ala - Lys(biotin) - OH
Material Safety Data Sheets (MSDS)
