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Peptides  >  p53 Peptides  >>  [Lys(Me2)382]-p53 (377-387); p53K382Me2

Product Name [Lys(Me2)382] - p53 (377 - 387); p53K382Me2
TSRHK - K(Me2) - LMFKT
Size 1 mg
Catalog # AS-65085-1
US$ $330
Purity % Peak Area By HPLC ≥ 95%
Description

p53K382Me2 is derived from amino acid residues 377-387 of human p53 tumor suppressor protein, with dimethylation at Lys382. DNA damage induces increased levels of this peptide, which is recognized by p53-binding protein 1 (53BP1). 53BP1 interacts with p53 and modulates its transactivation.

Storage -20C
References Kachirskaia, I. et al. J Biol Chem 283, 34660 (2008).
Molecular Weight 1404.7
Sequence
(One-Letter Code)
TSRHK-K(Me2)-LMFKT
Sequence
(Three-Letter Code)
H - Thr - Ser - Arg - His - Lys - Lys(Me2) - Leu - Met - Phe - Lys - Thr - OH
     
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