This peptide is derived from apolipoprotein E4. Apolipoprotein is a plasma protein present in various organs, such as the spleen, kidney, liver, and brain that binds low-density lipoprotein receptors and participates in cholesterol transport and redistribution. Apoliprotein E also functions in peripheral nerve injury and regeneration, immunoregulation, and regulation of cell growth and differentiation. Apolipoprotein E4 has been implicated in sporadic and late onset Alzheimer’s disease.
Storage
-20°C
References
Candiano, G. et al, Electrophoresis22, 1819 (2001); Poirier, J. et al. Proc Natl Acad Sci92, 12260 (1995); Mahley, RW. Science240, 622 (1988).
Molecular Weight
1730.9
Sequence (One-Letter Code)
SELEEQLTPVAEETR
Sequence (Three-Letter Code)
H - Ser - Glu - Leu - Glu - Glu - Gln - Leu - Thr - Pro - Val - Ala - Glu - Glu - Thr - Arg - OH
