This peptide is histone H3 (1-24) acetylated at Lys14 and Lys23, with a C-terminal GG linker followed by a biotinylated Lys. Lysine acetylation of histone H3 is associated with histone H4 methylation and has been implicated in transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Garcia, B. et al. Nat Methods4, 487 (2007).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg - Lys - Ser - Thr - Gly - Gly - Lys(Ac) - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Thr - Lys(Ac) - Ala - Gly - Gly - Lys(Biotin) - OH