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Peptides  >  p53 Peptides  >>  [Lys(Me1)373]-p53 (368-393), p53 K373(Me1), biotin-labeled, human

Product Name [Lys(Me1)373] - p53 (368 - 393), p53 K373(Me1), biotin - labeled, human
Biotin - KGWHLKS - K(Me1) - KGQSTSRHKKLMFKTEGPDSD - NH2
Size 0.25 mg
Catalog # 65324-025
US$ $140
Purity % Peak Area By HPLC ≥ 95%
Description

This is human tumor suppressor protein p53 (368-393) monomethylated at Lys373 and biotinylated through a KGW linker at its N-terminus. Methylation at Lys373 is catalyzed by G9a and Glp lysine methyltransferases and is associated with inactive p53.

Storage -20C
References Krishnan, S. et al. ChemBioChem 12, 254 (2011); Huang, J. et al. J Biol Chem 285, 9636 (2010).
Molecular Weight 3582.2
Sequence
(One-Letter Code)
Biotin-KGWHLKS-K(Me1)-KGQSTSRHKKLMFKTEGPDSD-NH2
Sequence
(Three-Letter Code)
Biotin - Lys - Gly - Trp - His - Leu - Lys - Ser - Lys(Me1) - Lys - Gly - Gln - Ser - Thr - Ser - Arg - His - Lys - Lys - Leu - Met - Phe - Lys - Thr - Glu - Gly - Pro - Asp - Ser - Asp - NH2
     
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