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Peptides  >  p53 Peptides  >>  [Lys(Me2)370]-p53 (361-380); p53K370Me2

Product Name [Lys(Me2)370] - p53 (361 - 380); p53K370Me2
Size 1 mg
Catalog # 65061-1
US$ $350
Purity % Peak Area By HPLC ≥ 95%
Description

p53K370Me2 is derived from amino acid residues 361-380 of human p53 tumor suppressor protein, with dimethylation at Lys370. This peptide promotes p53 interactions with both p21gene promoters and p53 binding protein 1 (53BP1), activating transcription of p53 target genes.

Storage -20°C
References Egorova, K. Biochem 75, 535 (2010).
Molecular Weight 2204.4
Sequence
(One-Letter Code)
GSRAHSSHL-K(Me2)-SKKGQSTSRH
Sequence
(Three-Letter Code)
H - Gly - Ser - Arg - Ala - His - Ser - Ser - His - Leu - Lys(Me2) - Ser - Lys - Lys - Gly - Gln - Ser - Thr - Ser - Arg - His - OH
     
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