This peptide is histone H2B (1-22) phosphorylated at Ser32, followed by a C-terminal GGK linker, with biotinylation on the epsilon side chain of Lys. Phosphorylation of histone H2B is associated with apoptotic cells and plays a role in caspase-initiated cell death. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.
Storage
-20°C
References
Ajiro, K. J Biol Chem275, 439 (2000).
Molecular Weight
3104.6
Sequence (One-Letter Code)
AQKKDGKKRKR-pS-RKESYSIYVGG-K(Biotin)
Sequence (Three-Letter Code)
H - Ala - Gln - Lys - Lys - Asp - Gly - Lys - Lys - Arg - Lys - Arg - pSer - Arg - Lys - Glu - Ser - Tyr - Ser - Ile - Tyr - Val - Gly - Gly - Lys(Biotin) - OH
