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Peptides  >  Histones  >  Histone H4 Peptides  >>  [Arg(Me2a)3]-Histone H4 (1-23)-GGK(Biotin)

Product Name [Arg(Me2a)3] - Histone H4 (1 - 23) - GGK(Biotin)
SG - R(Me2a) - GKGGKGLGKGGAKRHRKVLRGG - K(Biotin)
Size 0.25 mg
Catalog # AS-65278-025
US$ $120
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is histone H4 (1-23) asymmetrically dimethylated at Arg3 followed by a biotinylated Lys conjugated to a C-terminal GG linker. Methylation of Arg3 is catalyzed by PRMT1 and functions to promote p300 acetylation of histone H4. Dimethylation at Arg3 also activates transcription of estrogen-regulated genes. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Arita, K. et al. Proc Natl Acad Sci ,b>103, 5291 (2006); Wang, H. et al. Science 293, 853 (2001).
Molecular Weight 2857.4
Sequence
(One-Letter Code)
SG-R(Me2a)-GKGGKGLGKGGAKRHRKVLRGG-K(Biotin)
Sequence
(Three-Letter Code)
H - Ser - Gly - Arg(Me2a) - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - Leu - Arg - Gly - Gly - Lys(Biotin) - OH
     
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