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Peptides  >  Histones  >  Histone H4 Peptides  >>  [Arg(Me2a)3]-Histone H4(1-21)-GGK(Biotin), H4R3(Me2a), biotin-labeled

Product Name [Arg(Me2a)3] - Histone H4(1 - 21) - GGK(Biotin), H4R3(Me2a), biotin - labeled
Ac - SG - R(Me2a) - GKGGKGLGKGGAKRHRKVGG - K(Biotin)
Size 1 mg
Catalog # 64976-1
US$ $350
Purity % Peak Area By HPLC ≥ 95%
Description

This peptide is histone H4 amino acid residues 1 to 21. It is asymmetrically dimethylated at Arg3 with both methyl groups added to one nitrogen of the guanidinium group, and also contains a C-terminal GG linker, followed by a biotinylated Lys. Methylation of histone H4 at Arg3 is an important step in transcriptional activation, and allows for subsequent acetylation of H4 tails by p300. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Wang, H. et al. Science 293, 853 (2001).
Molecular Weight 2630.14
Sequence
(One-Letter Code)
Ac-SG-R(Me2a)-GKGGKGLGKGGAKRHRKVGG-K(Biotin)
Sequence
(Three-Letter Code)
Ac - Ser - Gly - Arg(Me2a) - Gly - Lys - Gly - Gly - Lys - Gly - Leu - Gly - Lys - Gly - Gly - Ala - Lys - Arg - His - Arg - Lys - Val - Gly - Gly - Lys(Biotin) - OH
     
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