This peptide is a tandem repeat dimer of apolipoprotein E (161-169). ApoE is important in the brain’s response to acute damage and plays a role in neuronal regeneration, neurite outgrowth, and synapse formation. ApoE has also been associated with b-amyloid deposits in brains of Alzheimer’s patients. This peptide can be used to study the signaling pathways stimulated by ApoE.
Kashverov, I. et al. Curr Pharm Des15, 2430 (2009); Hoe, H-S. et al Mol Brain Res137, 31 (2005).
Sequence (One-Letter Code)
Sequence (Three-Letter Code)
H - Leu - Arg - Lys - Leu - Arg - Lys - Arg - Leu - Leu - Leu - Arg - Lys - Leu - Arg - Lys - Arg - Leu - Leu - OH