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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Arg(Me2s)8]-Histone H3 (1-21), biotin-labeled

Product Name [Arg(Me2s)8] - Histone H3 (1 - 21), biotin - labeled
ARTKQTA - R(Me2s) - KSTGGKAPRKQLA - K(Biotin)
Size 1 mg
Catalog # AS-65351-1
US$ $350
Purity % Peak Area By HPLC ≥ 95%
Description

This is histone H3 (1-21) symmetrically dimethylated at Arg8 with a methyl group added to each nitrogen of the guanidinium group. This peptide is biotinylated at the epsilon side chain of an additional C-terminal Lys. Methylation at Arg8 blocks G9a methylation of Lys9. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Rathert, P. et al. Nat Chem Biol 4, 344 (2008).
Molecular Weight 2637.1
Sequence
(One-Letter Code)
ARTKQTA-R(Me2s)-KSTGGKAPRKQLA-K(Biotin)
Sequence
(Three-Letter Code)
H - Ala - Arg - Thr - Lys - Gln - Thr - Ala - Arg(Me2s) - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Arg - Lys - Gln - Leu - Ala - Lys(Biotin) - OH
Product Citations Mann, M. et al. (2013). PELP1 oncogenic functions involve CARM1 regulation. Carcinogenesis 34, 1468. doi: 10.1093/carcin/bgt091.
     
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