Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Me3)27-Histone H3 (23-34)-GGK(Biotin)

Product Name [Lys(Me3)27 - Histone H3 (23 - 34) - GGK(Biotin)
KAAR - K(Me3) - SAPATGGGG - K(Biotin)
Size 1 mg
Catalog # 65397
US$ $210
Purity % Peak Area By HPLC ≥ 95%
Description

This is histone H3 (23-34) trimethylated at Lys27 and biotinylated on the C-terminus through a GGK linker. Trimethylation of Lys27 promotes Polycomb protein (Pc)-chromatin association. This modification has also been shown to be associated with methylated CpG island genes in cancer cells. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Schlesinger, Y. et al. Nat Genet 39, 232 (2007); Zhang, X. et al. Nat Struct Mol Biol 14, 869 (2007); Min, J. et al. Genes Dev 17, 1823 (2003).
Molecular Weight 1624.9
Sequence
(One-Letter Code)
KAAR-K(Me3)-SAPATGGGG-K(Biotin)
Sequence
(Three-Letter Code)
H - Lys - Ala - Ala - Arg - Lys(Me3) - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Gly - Gly - Lys(Biotin) - OH
     
  < Back