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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Cit 2/8/17]-Histone H3 (1-21)-GGK(Biotin), amide

Product Name [Cit 2/8/17] - Histone H3 (1 - 21) - GGK(Biotin), amide
A - Cit - TKQTA - Cit - KSTGGKAP - Cit - KQLAGG - K(Biotin) - NH2
Size 0.25 mg
Catalog # 65404
US$ $250
Purity % Peak Area By HPLC ≥ 95%
Description

This is histone H3 (1-21) with deimination of Arg2, Arg8, and Arg17 to Citrulline (Cit). Its C-terminal is biotinylated through a GGK linker and blocked by an amide group. Deimination by peptidyl arginine deiminase 4 (PADI4) prevents methylation at these sites and blocks transcriptional activation. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Cuthbert, G. et al. Cell 118, 545 (2004).
Molecular Weight 2725.2
Sequence
(One-Letter Code)
A-Cit-TKQTA-Cit-KSTGGKAP-Cit-KQLAGG-K(Biotin)-NH2
Sequence
(Three-Letter Code)
H - Ala - Cit - Thr - Lys - Gln - Thr - Ala - Cit - Lys - Ser - Thr - Gly - Gly - Lys - Ala - Pro - Cit - Lys - Gln - Leu - Ala - Gly - Gly - Lys(Biotin) - NH2
     
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