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Peptides  >  Histones  >  Histone H3 Peptides  >>  [Lys(Me3)27]-Histone H3 (21-44), biotin-labeled

Product Name [Lys(Me3)27] - Histone H3 (21 - 44), biotin - labeled
ATKAAR - K(Me3) - SAPATGGVKKPHRYRPG - K(Biotin)
Size 1 mg
Catalog # AS-65347-1
US$ $305
Purity % Peak Area By HPLC ≥ 95%
Description

This is histone H3 (21-44) trimethylated at Lys27 with an additional C-terminal Lys and biotinylation on the epsilon side chain of this Lys. Trimethylation of Lys27 promotes Polycomb protein (Pc)-chromatin association and is associated with heterochromatin assembly and gene silencing. Provided at >95% peptide purity, this peptide was dissolved in distilled water at 1 mg/ml and re-lyophilized to powder form.

Storage -20C
References Zhang, X. et al. Nat Struct Mol Biol 14, 869 (2007); Min, J. et al. Genes Dev 17, 1823 (2003).
Molecular Weight 2902.4
Sequence
(One-Letter Code)
ATKAAR-K(Me3)-SAPATGGVKKPHRYRPG-K(Biotin)
Sequence
(Three-Letter Code)
H - Ala - Thr - Lys - Ala - Ala - Arg - Lys(Me3) - Ser - Ala - Pro - Ala - Thr - Gly - Gly - Val - Lys - Lys - Pro - His - Arg - Tyr - Arg - Pro - Gly - Lys(Biotin) - OH
     
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