This is histone H3 (23-31). Lys27 within this sequence is methylated by the polycomb group protein EZH2. Overexpression of EXH2 is associated with several human cancer lines, such as prostate and breast cancer.
Storage
-20°C
References
Kuzmichev, A. et al. Mol Cell14, 183 (2004); Kleer, C. et al. Proc Natl Acad Sci USA100, 11606 (2003); Varambally, S. et al. Nature419, 624 (2002).
Molecular Weight
899.1
Sequence (One-Letter Code)
KAARKSAPA
Sequence (Three-Letter Code)
H - Lys - Ala - Ala - Arg - Lys - Ser - Ala - Pro - Ala - OH