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Peptides  >  Cyclic Peptides  >   Disulfide Cyclized Peptides  >>  C-Type Natriuretic Peptide (32-53), human, porcine

Product Name C - Type Natriuretic Peptide (32 - 53), human, porcine
GLSKGCFGLKLDRIGSMSGLGC (Disulfide bridge: 6 - 22)
Size 1 mg
Catalog # AS-24244
US$ $220
Purity % Peak Area By HPLC ≥ 95%
Description

C-type Natriuretic Peptide (CNP), identified in 1990 and called C-type (in order to maintain the alphabetical nomenclature of natriuretic peptides), is the most highly conserved of natriuretic peptides between species. It is derived from a 126 amino acid preprohormone. CNP exists in two mature forms, one found in tissues, another in plasma and cerebrospinal fluid. It is present in high concentration of the vascular tree, especially the endothelium, central nervous tissues, and renal tubular cells. It is a powerful vasorelaxant and inhibitor of smooth muscle cell proliferation and may play a role in coagulation and fibrinogenesis by modulating endothelial cells.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C
References Ref: Kalra, P. et al. Eur. Heart J. 22, 997 (2001); Sudoh, T. et al. Biochem. Biophy. Res. Commun. 168, 863 (1990); Koller, KJ. et al. Science 252, 120 (1991).
Molecular Weight 2197.7
Sequence
(One-Letter Code)
GLSKGCFGLKLDRIGSMSGLGC (Disulfide bridge: 6-22)
Sequence
(Three-Letter Code)
H - Gly - Leu - Ser - Lys - Gly - Cys - Phe - Gly - Leu - Lys - Leu - Asp - Arg - Ile - Gly - Ser - Met - Ser - Gly - Leu - Gly - Cys - OH (Disulfide bridge: 6 - 22)
     
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