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Peptides  >  Tau Peptides  >>  Tau Peptide (45-73) (Exon 2/Insert 1 domain)

Product Name Tau Peptide (45 - 73) (Exon 2/Insert 1 domain)  NEW
ESPLQTPTEDGSEEPGSETSDAKSTPTAE
Size 1 mg
Catalog # 65431-1
US$ $58
Purity Peak Area by HPLC ≥95%
Description

TAU proteins belong to the microtubule-associated protein (MAP) family and are involved in the pathogenesis of Alzheimer’s disease. In the human brain, there are six TAU isoforms ranging from 352 to 441 amino acids in length. These isoforms vary at the carboxyl terminal according to the presence of either three repeat (3R) or four repeat (R4) domains, in addition to the presence or absence of one or two insert domains at the amino-terminus (see figure below). Tau Peptide (45-73) is a 29-amino acid long peptide derived from the Exon 2/Insert 1 domain.

RELATED PRODUCTS:

Tau Peptide (74-102) (Exon 3/Insert 2 domain)
Tau Peptide (244-274) (Repeat 1 domain)
Tau Peptide (275-305) (Repeat 2 domain)
Tau Peptide (306-336) (Repeat 3 domain)
Tau Peptide (337-368) (Repeat 4 domain)


Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
References Buee, L. et al. Brain Res Rev 33 95 (2000).
Trinczek, B. et al. Mol Biol Cell 6, 1887 (1995).
Molecular Weight 2977.97
Sequence
(One-Letter Code)
ESPLQTPTEDGSEEPGSETSDAKSTPTAE
Sequence
(Three-Letter Code)
Glu - Ser - Pro - Leu - Gln - Thr - Pro - Thr - Glu - Asp - Gly - Ser - Glu - Glu - Pro - Gly - Ser - Glu - Thr - Ser - Asp - Ala - Lys - Ser - Thr - Pro - Thr - Ala - Glu - OH
     
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