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Peptides  >  Apoptosis Peptides  >>  SensoLyte® AFC Caspase Substrate Sampler Kit *Fluorimetric*

Product Name SensoLyte® AFC Caspase Substrate Sampler Kit *Fluorimetric*
Size 1 kit
Catalog # 71117
US$ $501
Description

Caspases play important roles in apoptosis and cell signaling. They are also identified as drug-screening targets. AFC-based substrates yield blue fluorescence upon protease cleavage (Ex/Em=380 nm/500 nm). They are widely used to monitor caspase activity. The SensoLyte® Caspase Substrate Kit contains a series of AFC-based peptide substrates as fluorogenic indicators for assaying caspase protease activities. It provides the best solution for identifying a suitable substrate for designing AFC-based caspase assays. All the components in the kit are available in bulk package. The kit contains: • 8 AFC caspase substrates • Assay buffer • AMC (fluorescence reference standard for calibration) • A detailed protocol

Kit Size: 8 x 100 assays

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
Product Citations Twiner, MJ. et al. (2012). Induction of apoptosis pathways in several cell lines following exposure to the marine algal toxin Azaspiracid. Chem Res Toxicol 25, 1493.
Gugliesi, F. et al. (2010). The proapoptotic activity of the Interferon-inducible gene IFI16 provides new insights into its etiopathogenetic role in autoimmunity. J Autoimmun doi:10.1016/j.jaut.2010.04.001.
     
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