Fibronectin Fragments

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Peptides > Fibronectin Fragments

Fibronectin (FN) is found in interstitial matrix, on cell surfaces, plasma and other body fluids. It is a large multidomain glycoprotein that interacts with a variety of macromolecules including components of the cytoskeleton and the extracellular matrix, circulating components of the blood clotting, fibrinolytic, acute phase and complement systems, and with cell-surface receptors on a variety of cells including fibroblasts, neurons, phagocytes, and bacteria. FN also interacts with itself and binds several small molecules such as gangliosides and sugars. It appears to play a role in cellular migration during wound healing and development. FN expression regulates angiogenesis and vasculogenesis and participates in brain tissue responses to ischemia and seizures. The central cell-binding domain of FN through the RGD (Arg-Gly-Asp) sequence is important for cell adhesion.

Ref: Kim, JH. et al. J. Biol. Chem. 279, 41706 (2004); Comi, A. et al. Pediatric Res. 53, 762 (2003); Hynes, RO. Fibronectins (1990); (N.Y. Springer-Verlag); Sonmez, H. et al. Cancer Biochem. Biophys. 15, 107 (1995).

Product	Size	Catalog #	US$
[Glu3] - RGES, Control for RGD Peptides RGES	1 mg	62527	$61

Cyclo ( - GRGDSP) GRGDSP, N to C cyclized	1 mg	61110	$61

Cyclo ( - GRGDSP) GRGDSP, N to C cyclized	5 mg	61110-5	$242

Cyclo ( - RADfE), RGD negative control Cyclo( - RADfE - )	1 mg	62352	$110

Cyclo ( - RADfK - ), RGD negative control Cyclo( - RADfK - )	1 mg	62351	$110

Cyclo ( - RGDfK) Cyclo( - RGDfK)	1 mg	61111	$93

Cyclo ( - RGDyK) Cyclo( - RGDyK)	1 mg	61183-1	$66

Cyclo ( - RGDyK) Cyclo( - RGDyK)	5 mg	61183-5	$193

Cyclo (RGDfC), a_vb₃ Integrin Binding Cyclic RGD Peptide Cyclo( - RGDfC)	1 mg	63785-1	$71

Cyclo [ - RGDyK(HiLyte Fluor™ 750)] Cyclo[ - RGDy - K(Hilyte Fluor™ 750)]	0.1 mg	62333-01	$303

Cyclo [ - RGDyK(HiLyte Fluor™ 750)] Cyclo[ - RGDy - K(Hilyte Fluor™ 750)]	1 mg	62333-1	$1452

Cyclo - [GRGESP] Cyclo - [GRGESP]	1 mg	64447	$83

Cyclo[ - RGDy - K(5 - FAM)] Cyclo[ - RGDy - K(5 - FAM)]	1 mg	65160	$181

Fibrinolysis Inhibiting Factor GPRP	5 mg	24262	$99

GRGDS GRGDS	5 mg	61107	$61

GRGDS, amide GRGDS - NH2	5 mg	61108	$61

GRGDS, LC - biotin labeled Biotin - LC - GRGDS	1 mg	62347	$77

GRGDSP GRGDSP	1 mg	22945	$22

GRGDSP GRGDSP	5 mg	22946	$99

GRGDSPK GRGDSPK	1 mg	61109	$71

GRGDTP GRGDTP	1 mg	22947	$39

GRGDTP GRGDTP	5 mg	22948	$143

GRGESP GRGESP	1 mg	22949	$39

GRGESP GRGESP	5 mg	22950	$143

Integrin Binding Peptide Ac - GCGYGRGDSPG - NH2	1 mg	62349	$77

RGD - targeted Proapoptotic Peptide ACDCRGDCFC - GG - klaklakklaklak - NH2 (S - S bonded C1 - C4 & C2 - C3)	1 mg	62207	$363

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