Glucagon-Like Peptides

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Peptides > Glucagon-Like Peptides

Processed from a 160-amino acid proglucagon precursor, Glucagon is produced in the A-cells of the Islets of Langerhans, in the L cells of the intestinal mucosa and in specialized neurons of the central nervous system (mainly in the hypothalamus and in the medulla oblongata). It functions as a counter-regulatory hormone that opposes the actions of insulin and maintains the levels of blood glucose, particularly in patients with hypoglycemia. Glucagon regulates glucose homeostasis through enhanced synthesis and mobilization of glucose in the liver. Besides possessing insulinotropic properties and direct action on satiety center in the brain, GLP-1 may be the main hormone regulating the amount of ingested food and water.

Ref: Yamamoto, H. et al. J. Neurosci. 23, 2939 (2003); Creutzfeldt, W. et al. Exp. Clin. Endocrinol. Diabetes. 109, S288 (2001); Jin, SL. et al. J. Comp. Neurol. 271, 9 (1988); Turton, MD. et al. Nature 379, 69 (1996); Dalle, S. et al. J. Biol. Chem. 274, 10869 (1999); Tomasik, PJ. et al. Horm. Metab. Res. 34, 77 (2002); Iwasaki, Y. et al. J. Gastroenterol. 39, 831 (2004); Tang-Christensen, M. et al. Diabetes. 47, 530 (1998); Leonova, J. et al. Am. J. Physiol. Cell Physiol. 281, C1495 (2001); Rönnbäck, L. and E. Hansson, J. Neuroinflam. 1, 22 (2004); Rothstein, JD. et al. Neuron. 16, 675 (1996); Sonnewald, U. et al. Pharmacol. 301, 1 (2002).

Product	Size	Catalog #	US$
[FAM - Trp³¹] - GLP - 1 (7 - 36), Fluorescent label at Trp³¹ HAEGTFTSDVSSYLEGQAAKEFIA (Trp - S - FAM) - LVKGR - NH2	0.5 mg	64488	$357

Biotin - Glucagon (1 - 29), bovine, human, porcine Biotin - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	0.5 mg	60274-05	$143

Biotin - Glucagon (1 - 29), bovine, human, porcine Biotin - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	1 mg	60274-1	$242

Biotin - Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Biotin - HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	23586	$198

Biotin - Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Biotin - HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	23587	$335

GLP - 1(9 - 36), amide, human EGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	65070	$203

GLP - 2 (1 - 34), Glucagon - Like Peptide - 2 (1 - 34), human HADGSFSDEMNTILDNLAARDFINWLIQTKITDR	1 mg	62068	$297

Glucagon (1 - 18) HSQGTFTSDYSKYLDSRR	1 mg	64344-1	$110

Glucagon (1 - 29), bovine, human, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	0.5 mg	22456	$71

Glucagon (1 - 29), bovine, human, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	1 mg	22457	$127

Glucagon (1 - 29), bovine, human, porcine, FAM - labeled FAM - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	0.5 mg	60273-05	$143

Glucagon (1 - 29), bovine, human, porcine, FAM - labeled FAM - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	1 mg	60273-1	$242

Glucagon (1 - 37), Oxyntomodulin, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA	1 mg	22455	$665

Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	22462	$127

Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	22463	$231

Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRK(Biotin) - NH2	0.5 mg	23642	$275

Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRK(Biotin) - NH2	1 mg	23643	$457

Glucagon - Like Peptide 1, GLP - 1 (7 - 37) HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG	0.5 mg	20761	$154

Glucagon - Like Peptide 1, GLP - 1 (7 - 37) HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG	1 mg	20762	$275

Glucagon - Like Peptide 1, GLP - 1 amide, human HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	22460	$181

Glucagon - Like Peptide 1, GLP - 1 amide, human HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	22461	$335

Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled FAM - HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	23606	$291

Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled FAM - HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	23607	$484

Glucagon - like Peptide - 2, GLP - 2 (146 - 178), human HADGSFSDEMNTILDNLAARDFINWLIQTKITD	1 mg	62070	$281

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