Glucagon-Like Peptides

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Peptides > Glucagon-Like Peptides

Processed from a 160-amino acid proglucagon precursor, Glucagon is produced in the A-cells of the Islets of Langerhans, in the L cells of the intestinal mucosa and in specialized neurons of the central nervous system (mainly in the hypothalamus and in the medulla oblongata). It functions as a counter-regulatory hormone that opposes the actions of insulin and maintains the levels of blood glucose, particularly in patients with hypoglycemia. Glucagon regulates glucose homeostasis through enhanced synthesis and mobilization of glucose in the liver. Besides possessing insulinotropic properties and direct action on satiety center in the brain, GLP-1 may be the main hormone regulating the amount of ingested food and water.

Ref: Yamamoto, H. et al. J. Neurosci. 23, 2939 (2003); Creutzfeldt, W. et al. Exp. Clin. Endocrinol. Diabetes. 109, S288 (2001); Jin, SL. et al. J. Comp. Neurol. 271, 9 (1988); Turton, MD. et al. Nature 379, 69 (1996); Dalle, S. et al. J. Biol. Chem. 274, 10869 (1999); Tomasik, PJ. et al. Horm. Metab. Res. 34, 77 (2002); Iwasaki, Y. et al. J. Gastroenterol. 39, 831 (2004); Tang-Christensen, M. et al. Diabetes. 47, 530 (1998); Leonova, J. et al. Am. J. Physiol. Cell Physiol. 281, C1495 (2001); Rönnbäck, L. and E. Hansson, J. Neuroinflam. 1, 22 (2004); Rothstein, JD. et al. Neuron. 16, 675 (1996); Sonnewald, U. et al. Pharmacol. 301, 1 (2002).

Product	Size	Catalog #	US$
[Des - His1, Glu9] - Glucagon (1 - 29), amide SQGTFTSEYSKYLDSRRAQDFVQWLMNT - NH2	0.5 mg	20765	$130
[Des - His1, Glu9] - Glucagon (1 - 29), amide SQGTFTSEYSKYLDSRRAQDFVQWLMNT - NH2	1 mg	20766	$200
[FAM - Trp³¹] - GLP - 1 (7 - 36) NEW HAEGTFTSDVSSYLEGQAAKEFIA (Trp - S - FAM)	0.5 mg	64488	$325
Biotin - Glucagon (1 - 29), bovine, human, porcine Biotin - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	0.5 mg	60274-05	$130
Biotin - Glucagon (1 - 29), bovine, human, porcine Biotin - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	1 mg	60274-1	$220
Biotin - Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Biotin - HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	23586	$180
Biotin - Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human Biotin - HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	23587	$305
GLP - 2 (1 - 34), Glucagon - Like Peptide - 2 (1 - 34), human HADGSFSDEMNTILDNLAARDFINWLIQTKITDR	1 mg	62068	$270
Glucagon (1 - 18) NEW HSQGTFTSDYSKYLDSRR	1 mg	64344-1	$100
Glucagon (1 - 29), bovine, human, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	0.5 mg	22456	$65
Glucagon (1 - 29), bovine, human, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	1 mg	22457	$115
Glucagon (1 - 29), bovine, human, porcine, FAM - labeled FAM - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	0.5 mg	60273-05	$130
Glucagon (1 - 29), bovine, human, porcine, FAM - labeled FAM - HSQGTFTSDYSKYLDSRRAQDFVQWLMNT	1 mg	60273-1	$220
Glucagon (1 - 37), Oxyntomodulin, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA	0.5 mg	22454	$330
Glucagon (1 - 37), Oxyntomodulin, porcine HSQGTFTSDYSKYLDSRRAQDFVQWLMNTKRNKNNIA	1 mg	22455	$605
Glucagon (146 - 178) NEW HADGSFSDEMSTILDNLATRDFINWLIQTKITD	1 mg	63916	$275
Glucagon (19 - 29), bovine, human, porcine AQDFVQWLMNT	1 mg	22458	$35
Glucagon (19 - 29), bovine, human, porcine AQDFVQWLMNT	5 mg	22459	$130
Glucagon - Like Peptide 1, GLP - 1 (7 - 17) - Cys HAEGTFTSDVSC	1 mg	60181-1	$65
Glucagon - Like Peptide 1, GLP - 1 (7 - 17) - Cys HAEGTFTSDVSC	5 mg	60181-5	$265
Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	22462	$115
Glucagon - Like Peptide 1, GLP - 1 (7 - 36), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	22463	$210
Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRK(Biotin) - NH2	0.5 mg	23642	$250
Glucagon - Like Peptide 1, GLP - 1 (7 - 36) - Lys(Biotin), amide, human HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRK(Biotin) - NH2	1 mg	23643	$415
Glucagon - Like Peptide 1, GLP - 1 (7 - 37) HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG	0.5 mg	20761	$140
Glucagon - Like Peptide 1, GLP - 1 (7 - 37) HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG	1 mg	20762	$250
Glucagon - Like Peptide 1, GLP - 1 amide, human HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	22460	$165
Glucagon - Like Peptide 1, GLP - 1 amide, human HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	22461	$305
Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled FAM - HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	0.5 mg	23606	$265
Glucagon - Like Peptide 1, GLP - 1 amide, human, FAM - labeled FAM - HDEFERHAEGTFTSDVSSYLEGQAAKEFIAWLVKGR - NH2	1 mg	23607	$440
Glucagon - like Peptide - 2, GLP - 2 (1 - 34), rat HADGSFSDEMNTILDNLATRDFINWLIQTKITDR	1 mg	62069	$270
Glucagon - like Peptide - 2, GLP - 2 (146 - 178), human HADGSFSDEMNTILDNLAARDFINWLIQTKITD	1 mg	62070	$255
Glucagon - like Peptide - 2, GLP - 2 (146 - 178), rat HADGSFSDEMNTILDNLATRDFINWLIQTKITD	1 mg	62067	$255
Peptide Histidine Isoleucinamide (PHI), Porcine (1 - 27) NEW HADGVFTSDFSRLLGQLSAKKYLESLI - NH2	1 mg	64125	$195
Peptide Histidine Isoleucinamide (PHI), Rat (1 - 27) NEW HADGVFTSDYSRLLGQISAKKYLESLI - NH2	1 mg	64126	$195

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