Amylin Peptides

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Peptides > Amylin Peptides

The islet amyloid polypeptide (IAPP), or amylin, is a 37 amino acid peptide identified in 1987. Amylin is the major and unique component of islet b-amyloid. Amylin is ~45% homologous with calcitonin gene-related peptide (CGRP). The (20-29) fragment of amylin is critical to the pathogenesis of islet amyloid. A pathologic feature of 90% of persons with Type 2 diabetes is the presence of islet amyloid deposits. These deposits are thought to contribute to pancreatic b cell dysfunction, either by direct cytotoxicity or by reducing b cell mass. Amylin is co-secreted with insulin.

Ref: Kahn, SE. et al. Diabetes l. 48, 241 (1999); Bennett, R. et al. J. Biol. Chem. 275, 36621 (2000).

Product	Size	Catalog #	US$
β - Amyloid (12 - 24) VHHQKLVFFAEDV	1 mg	62883	$83

β - Amyloid (13 - 23) HHQKLVFFAED	1 mg	62882	$77

[Ala^16,17,20] - β - Amyloid (1 - 28) DAEFRHDSGYEVHHQAAVFAAEDVGSNK	1 mg	62890	$225

[NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22 - 27) NF - (NMe - G) - A - (NMe - I) - L	1 mg	61937	$220

Amylin (1 - 37), human KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (Disulfide bridge: 2 - 7)	1 mg	60804	$303

Amylin (1 - 37), human, amide KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)	1 mg	60254-1	$240

Amylin (1 - 37), rat KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)	0.5 mg	60253-05	$303

Amylin (1 - 37), rat KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)	1 mg	60253-1	$479

Amylin (20 - 29), human SNNFGAILSS	1 mg	60259-1	$71

Amylin (8 - 37), human ATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2	0.5 mg	21747-05	$143

Amylin (8 - 37), human ATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2	1 mg	21747	$242

Amylin (8 - 37), rat ATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2	0.5 mg	21749-05	$143

Amylin (8 - 37), rat ATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2	1 mg	21749	$242

Beta - Amyloid (13 - 22) HHQKLVFFAE	1 mg	62894	$77

Biotin - Amylin (1 - 37), amide, human Biotin - KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2 (disulfide bridge: 2 - 7)	0.5 mg	64451-05	$193

Pramlintide, Acetate [Pro25, 28, 29] - Amylin(1 - 37), human, Amide KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY - NH2 (S - S Bond) acetate salt	1 mg	64576-1	$269

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