Peptides  >  Amylin Peptides
The islet amyloid polypeptide (IAPP), or amylin, is a 37 amino acid peptide identified in 1987. Amylin is the major and unique component of islet b-amyloid. Amylin is ~45% homologous with calcitonin gene-related peptide (CGRP). The (20-29) fragment of amylin is critical to the pathogenesis of islet amyloid. A pathologic feature of 90% of persons with Type 2 diabetes is the presence of islet amyloid deposits. These deposits are thought to contribute to pancreatic b cell dysfunction, either by direct cytotoxicity or by reducing b cell mass. Amylin is co-secreted with insulin.

Ref: Kahn, SE. et al. Diabetes l. 48, 241 (1999); Bennett, R. et al. J. Biol. Chem. 275, 36621 (2000).
 Product Size Catalog # US$  
[NMeG24, NMeI26] Human Islet Amyloid Polypeptide (IAPP) (22 - 27)
NF - (NMe - G) - A - (NMe - I) - L
1 mg AS-61937 $220
Amylin (1 - 37), human
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY (Disulfide bridge: 2 - 7)
1 mg AS-60804 $303
Amylin (1 - 37), human, amide
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)
1 mg AS-60254-1 $240
Amylin (1 - 37), rat
KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)
0.5 mg AS-60253-05 $303
Amylin (1 - 37), rat
KCNTATCATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2 (Disulfide bridge: 2 - 7)
1 mg AS-60253-1 $479
Amylin (20 - 29), human
SNNFGAILSS
1 mg AS-60259-1 $71
Amylin (8 - 37), rat
ATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2
0.5 mg AS-21749-05 $143
Amylin (8 - 37), rat
ATQRLANFLVRSSNNLGPVLPPTNVGSNTY - NH2
1 mg AS-21749 $242
Biotin - Amylin (1 - 37), amide, human
Biotin - KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY - NH2 (disulfide bridge: 2 - 7)
0.5 mg AS-64451-05 $193
Pramlintide, Acetate [Pro25, 28, 29] - Amylin(1 - 37), human, Amide
KCNTATCATQRLANFLVHSSNNFGPILPPTNVGSNTY - NH2 (S - S Bond) acetate salt
1 mg AS-64576-1 $269
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