Ghrelins and Obestatins

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Peptides > Ghrelins and Obestatins

Ghrelin is a 28-amino-acid peptide hormone produced by the stomach in mammals. The major active form of Ghrelin is a peptide with an n-octanoyl modification at Ser3 (n-octanoyl Ghrelin). Endogenous Ghrelin participates in the regulation of food intake and body weight. The secretion of ghrelin is augmented under conditions of both gastric emptying and filling, and the release is stimulated by intestinal hormones. Ghrelin is also involved in the release of growth hormone from the anterior pituitary through activation of the growth hormone secretagogue receptor (GHS-R). It is also a potent vasodilator that can be detected in endothelial cells of arteries and veins in human.

Ref: Kojima, M. et al. Nature 402, 656 (1999); Kleinz, MJ. et al. Cardiovasc Res. 69, 227 (2006); Richards, M. at al. Gen. Comp. Endocrinol. Oct 2005; Murakami, N. et al. J. Endocrinol. 174, 283 (2002); Nishi, Y. et al. Endocrinol. 146, 2709 (2005).

Product	Size	Catalog #	US$
[Des - octanoyl] - Ghrelin, human GSSFLSPEHQRVQQRKESKKPPAKLQPR	1 mg	61177	$220

[Des - octanoyl] - Ghrelin, rat GSSFLSPEHQKAQQRKESKKPPAKLQPR	1 mg	60981	$220

Biotin - Ghrelin, human Biotin - GS - S(n - octanoyl) - FLSPEHQRVQQRKESKKPPAK LQPR	1 mg	29391	$363

Ghrelin, human GS - S(n - octanoyl) - FLSPEHQRVQQRKESKKPPAKLQPR	1 mg	24157	$242

Ghrelin, human GS - S(n - octanoyl) - FLSPEHQRVQQRKESKKPPAKLQPR	5 mg	24158	$968

Ghrelin, rat GS - S(n - octanoyl) - FLSPEHQKAQQRKESKKPPAKLQPR	1 mg	24159	$242

Ghrelin, rat GS - S(n - octanoyl) - FLSPEHQKAQQRKESKKPPAKLQPR	5 mg	24160	$968

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