MOG Peptides, Assays & Antibodies


AnaSpec is pleased to support advances in MS research by providing MOG (35 - 55), mouse, rat, a key peptide that induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice. AnaSpec's MOG (35-55) peptide from mouse and rat sequence (cat# 60130) has been shown to induce anti-MOG (35-55) autoantibody production in C57BL/6 mice at 100% incidence (10/10), indicating that this peptide is the clear choice for in vivo anti-MOG (35-55) autoantibody study. In addition to this peptide, we also provide a large selection of MOG peptides of varied sequences and lengths.

AnaSpec also provides MBP (myelin basic protein) and PLP (proteolipid proteins) peptides, two other potential primary encephalitogenic target antigens in multiple sclerosis.

In addition to EAE/MS inducing peptides, AnaSpec also provides SensoLyte® Anti-Human MOG (35-55) and (1-125) IgG ELISA Kits for detection of anti-MOG (35-55 and (1-125) IgG, respectively. Anti-MOG antibodies are available as well.

MOG Peptides

Table 1. MOG (35-55), mouse/rat is available in 2 sizes. To obtain a price quote for larger quantity of the MOG (35-55) peptide, please email service@anaspec.com.

Product

Size

Catalog #

MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK

1 mg

AS-60130-1

MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK

5 mg

AS-60130-5



Table 2. A full listing of all MOG peptides.

Product

Size

Catalog #

MOG (1 - 21), rat
GQFRVIGPGHPIRALVGDEAE

1 mg

AS-64650

MOG (8 - 21)
PGYPIRALVGDEAE

1 mg

AS-62369

MOG (35 - 52)
MEVGWYRSPFSRVVHLYR

1 mg

AS-61603

MOG (35 - 55), human
MEVGWYRPPFSRVVHLYRNGK

1 mg

AS-63918

MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK

1 mg

AS-60130-1

MOG (35 - 55), mouse, rat
MEVGWYRSPFSRVVHLYRNGK

5 mg

AS-60130-5

MOG (40–54)
YRSPFSRVVHLYRNG

1 mg

AS-61626

MOG (43–54)
PFSRVVHLYRNG

1 mg

AS-61610

MOG (45 - 54)
SRVVHLYRNG

1 mg

AS-61611

MOG (50 - 74), human
LYRNGKDQDGDAPEYRGRTELLKD

1 mg

AS-64216

MOG (71 - 90), mouse
LLKETISEGKVTLRIQNVRF

1 mg

AS-64892

MOG (89 - 113), human
RFSDEGGFTCFFRDHSYQEEAAMEL

1 mg

AS-64218

MOG (91 - 108), rat
SDEGGYTCFFRDHSYQEE

1 mg

AS-62735

MOG (91 - 114), rat
SDEGGYTCFFRDHSYQEEAAVELK

1 mg

AS-62738

MOG (92–106)
DEGGYTCFFRDHSYQ

1 mg

AS-62732

MOG (101 - 120), human, mouse
RDHSYQEEAAMELKVEDPFY

1 mg

AS-62370

Myelin Oligodendrocyte Basic Protein (16 - 37); MOBP16 - 37, mouse
QKFSEHFSIHCCPPFTFLNSKR

1 mg

AS-65124

SensoLyte® Anti-MOG (1-125) & (35-55) IgG ELISA Quantitation Kits

  • 2-3 hours assay time at room temperature
  • FRETPeptide

  • 0.5-1 μl of serum or cerebrospinal fluid of test sample concentration
  • Colorimetric read-out at 450 nm
  • Kits have dynamic range of 8-500 ng/ml, except 55153-H (1.56-100 ng/ml)
  • Assay Kit
    Cat#
    SensoLyte® Anti-Human MOG (1-125) Human IgG Specific ELISA Kit
    SensoLyte® Anti-Human MOG (1-125) Mouse IgG Specific ELISA Kit
    SensoLyte® Anti-Human MOG (1-125) Rat IgG Specific ELISA Kit
    SensoLyte® Anti-Mouse MOG (1-125) IgG Quantitative ELISA Kit
    SensoLyte® Anti-Rat MOG (1-125) IgG Quantitative ELISA Kit
    SensoLyte® Anti-MOG (35 - 55) IgG Quantitative ELISA Kit (mouse/rat)
    FRETPeptide

    Anti-MOG Antibodies

    Antibody Species Reactivity Cat#
    Anti-MOG, mouse monoclonal clone B1A Human, Mouse, Rat AS-55914
    Anti-MOG, human, rabbit polyclonal Human, Mouse, Rat AS-55161
    Anti-MOG, mouse, rabbit polyclonal Human, Mouse AS-55160
    FRETPeptide
    Recombinant mouse MOG (1-125) protein (15 μg)(A) and crude mouse brain lysate (B) were immunoprecipitated with mouse anti-MOG (B1A) monoclonal antibody (Cat# AS-55914) and probed with rabbit anti-mouse MOG, polyclonal antibody (Cat# AS-55160). Secondary goat anti-rabbit IgG-HiLyte™ Fluor 750 nm labeled antibody (Cat# AS-61057-H750) was used at 1/25,000 dilution. Immunoreactive bands were detected at 14 kDa(A) and 27 kDa (B).


    Recombinant MOG Proteins

    Species Catalog #
    100 μg 500 μg 1000 μg
    Human AS-55158-100 AS-55158-500 AS-55158-1000
    Mouse AS-55150-100 AS-55150-500 AS-55150-1000
    Rat AS-55152-100 AS-55152-500 AS-55152-1000
    FRETPeptide

    Related Products:
    PLP Peptides and Anti-PLP Antibodies

    MBP Peptides and Anti-MBPs