Insulin Receptors Antibodies- New Optimized Size


Insulin Receptors Antibodies- New Optimized Size

The insulin receptor is a transmembrane receptor that belongs to the tyrosine kinase receptors class. It is a heterotetrameric glycoprotein composed of disulfide-linked subunits in a β-α-α-β configuration. This transmembrane receptor consists of 95kDa β-subunit, a single transmembrane domain, and 135kDa α-subunit, which is completely extracellular. Binding of insulin to the receptor results in stimulation of its intrinsic kinase activity. The insulin receptor mediates insulin action through the phosphorylation of substrate proteins. Insulin receptor becomes phosphorylated as a response to stimulation of cells by insulin, insulin-like growth factor (IGF-I) and interleukin 4. The major substrates of the insulin receptor kinase are the insulin receptor substrate (IRS) family of proteins, IRS-1, IRS-2, IRS-3, IRS-4. Recently, two more signaling proteins, IRS5/DOK4 and IRS6/DOK5, have been identified as potentially new members of the IRS family. The insulin receptor substrate-1 (IRS-1), a 170-185 kDa protein, is a major substrate of the insulin receptor. IRS-1 is phosphorylated on serine, threonine and tyrosine residues in a variety of tissues.

AnaSpec is pleased to showcase our line of insulin receptor antibodies; ideal for addressing your research needs in protein phosphorylation, glucose metabolism, cancer, and diabetes studies. Rigorously validated on ELISA, and Western Blot or IHC, and offered in an optimized research-grade size, AnaSpecs insulin receptor antibodies offer premium quality in a cost-effective package.

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Product New Size Catalog#
Anti-Insulin NEW50 g53585
Anti-Insulin Receptor NEW50 g53586
Anti-IRS-1 NEWInsulin Receptor Substrate-1 (IRS-1)50 g53594
Anti-IRS-1 (pSer312), phospho-specific 50 g 28120
Anti-IRS-1 (Paired312), non-phospho-specific 50 g 28121
Anti-IRS-2 (pSer731, phospho-specific 50 g 28122
Anti_IRS-2 (Paired 731), non-phospho-specific 50 g 28123
Anti-IGF-1 NEW Insulin-like growth factor 1 50 g 53566
Anti-IGF-1 NEWInsulin-like growth factor 2 50 g 53567
Anti-IRS-1
The antibody was raised against a synthetic peptide corresponding to human IRS-1 protein. Species Reactivity: human.
Image: Human colon carcinoma stained with Anti-IRS-1
50 g 53594
Anti-Insulin Receptor
Mouse anti-insulin receptor monoclonal antibody. Species Reactivity: human, cow, pig, rabbit, sheep.
Image: Human pancreas stained with Anti-Insulin receptor.
50 g 53586
Anti-Insulin
Mouse anti-insulin monoclonal antibody was raised against swine insulin. Species reactivity: human, rat, cow, pig, and rabbit.
Image: Human pancreas stained with Anti-Insulin antibody.
50 g 53585





Insulin Receptor Related Peptides

One of the world's largest providers of catalog peptides, AnaSpec also carries a number of high-purity insulin receptor (IRS) related peptides.




  • High Purity
  • Triple-Stage Validation by Mass Spec and HPLC
  • May be used as insulin receptor tyrosin kinase substrates


  • ProductSizeCat. #
    Insulin Receptor (1142-1153) 1 mg24537
    Insulin Receptor (1142-1153) 1mg24538
    Insulin Receptor (1142-1153), phosphorylated (Y1146) 1 mg 20292
    Insulin Receptor (1142-1153), phosphorylated (Y1146) 5 mg 24503
    Insulin Receptor (1142-1153), phosphorylated (Y1146), biotinylated 1 mg 23725
    Insulin Receptor (1142-1153), phosphorylated (Y1146), biotinylated 5 mg23726
    Insulin Receptor (1142-1153), phosphorylated (Y1146) 1 mg 20274
    Insulin Receptor (1142-1153), phosphorylated (Y1146)5 mg24501
    Insulin Receptor (1142-1153), phosphorylated (Y1146), biotinylated 1 mg23727
    Insulin Receptor (1142-1153), phosphorylated (Y1146), biotinylated 5 mg23728
    Insulin Receptor (1142-1153), phosphorylated (Y1151) 1 mg 20273
    Insulin Receptor (1142-1153), phosphorylated (Y1151) 5 mg 24502
    Insulin Receptor (1142-1153), phosphorylated (Y1151), biotinylated 1 mg 23729
    Insulin Receptor (1142-1153), phosphorylated (Y1151), biotinylated 5 mg 23730
    Insulin Receptor (1142-1153), phosphorylated (Y1151, Y1150, Y1151) 1 mg 20272
    Insulin Receptor (1142-1153), phosphorylated (Y1151, Y1150, Y1151) 5 mg 24500
    Insulin Receptor (1142-1153), phosphorylated (Y1151, Y1150, Y1151), biotinylated 1 mg 23910
    Insulin Receptor (1142-1153), phosphorylated (Y1151, Y1150, Y1151), biotinylated 5 mg 23911
    Insulin Receptor (1142-1153), amide 1 mg 27065
    Insulin Receptor (1142-1153), amide 5 mg 27066
    Insulin Receptor (1142-1153), biotinylated 1 mg 24629
    Insulin Receptor (1142-1153), biotinylated 5 mg 24840
    Insulin Receptor (1142-1153), amide, biotinylated 1 mg 23998
    Insulin Receptor (1142-1153), biotinylated 5 mg 23999
    Kinase Domain of Insulin Receptor (1) 1 mg 24544
    Kinase Domain of Insulin Receptor (1) 5 mg 61765
    IRS1-derived peptide NEW 1 mg 61764
    Insulin B (9-23) NEW 1 mg 61532
    Proinsulin C-Peptide (31-63), porcine 0.5 mg 61129
    Proinsulin C-Peptide (55-89), human 0.5 mg 61130