PAR Peptides Wide Selection


GPCR Peptides - PAR

With one of the world's most extensive collections of catalog peptides, AnaSpec is pleased to introduce our latest series of PAR peptides.

Protease or Proteinase-Activated Receptors, PARs, belong to the seven transmembrane G-protein coupled family of receptors.1 These receptors are activated when the amino terminus of the receptor is cleaved by specific serine proteases - thrombin (PAR-1, 3 and 4) and trypsin (PAR-2). 2 The cleaved amino end can then act as a tethered ligand on the second extracellular loop of the receptor thereby activating the receptor. 1 Short sequences contained in the amino terminus have been found to activate the receptors on their own, without the need for the protease cleavage.

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Product

Size

Catalog #

PAR-1 Agonist, STAL 2, amide
SFLLRN-NH2

5 mg

60679

PAR-1 Agonist, Thrombin Receptor Activator for Peptide 6 (TRAP - 6)
SFLLRN

1 mg

5 mg

24190

24191

Scrambled PAR-1 Agonist
FSLLRN-NH2

1 mg

5 mg

60197-1

60197-5

Thrombin Receptor (42 - 48) Agonist, human
SFLLRNP

1 mg

5 mg

24169

24170

Thrombin Receptor Agonist, amide
SFLLR-NH2

5 mg

60680

Thrombin Receptor Antagonist
FLLRN

5 mg

60678

SFLLRNPNDKYEPF, TRAP-14, Thrombin Receptor 42 - 55, human
SFLLRNPNDKYEPF

1 mg

5 mg

24171

24172

PAR-1 Agonist
TFLLRN

1 mg

61530

PAR-1 Agonist, amide
TFLLRN-NH2

5 mg

62937

PAR-1 Agonist, amide
TFLLRNPNDK-NH2

1 mg

62936

PAR-1 Agonist, amide
AYPGKF-NH2

1 mg

5 mg

60218-1

60218-5

PAR-2 Agonist, amide
SLIGKV-NH2

1 mg

5 mg

60217-1

60217-5

PAR-3 Agonist, amide
SFNGGP-NH2

1 mg

62938

PAR-4 Agonist, amide, human
GYPGQV-NH2

1 mg

60779

PAR-4 Agonist, amide, murine
GYPGKF-NH2

1 mg

60778

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Other Thrombin related Peptides

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References:

  1. Macfarlane, SR. et al. Pharmacol. Rev. 53, 245 (2001).
  2. Santulli, RJ. et al. PNAS 92, 9151 (1995).