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| PAR Peptides – Wide Selection |
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With one of the world’s most extensive collections of
catalog peptides, AnaSpec is pleased to introduce our latest series of PAR
peptides.
Protease or Proteinase-Activated Receptors, PARs, belong to the seven transmembrane
G-protein coupled family of receptors.1 These receptors are activated
when the amino terminus of the receptor is cleaved by specific serine proteases
- thrombin (PAR-1, 3 and 4) and trypsin (PAR-2). 2 The cleaved
amino end can then act as a tethered ligand on the second extracellular loop
of the receptor thereby activating the receptor. 1 Short sequences
contained in the amino terminus have been found to activate the receptors
on their own, without the need for the protease cleavage.
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here to request AnaSpec’s New Peptides Brochure.
| Product |
Size |
Catalog
# |
| PAR-1 Agonist, STAL – 2, amide
SFLLRN-NH2
|
5 mg |
60679 |
| PAR-1 Agonist, Thrombin Receptor Activator for Peptide 6 (TRAP
- 6)
SFLLRN
|
1 mg
5 mg |
24190
24191 |
| Scrambled PAR-1 Agonist
FSLLRN-NH2
|
1 mg
5 mg |
60197-1
60197-5 |
| Thrombin Receptor (42 - 48) Agonist, human
SFLLRNP
|
1 mg
5 mg |
24169
24170 |
| Thrombin Receptor Agonist, amide
SFLLR-NH2
|
5 mg |
60680 |
| Thrombin Receptor Agonist
SFLLR
|
1 mg
5 mg |
24026
24027 |
| Thrombin Receptor Antagonist
FLLRN
|
5 mg |
60678 |
| SFLLRNPNDKYEPF, TRAP-14, Thrombin Receptor 42 - 55, human
SFLLRNPNDKYEPF
|
1 mg
5 mg |
24171
24172 |
| PAR - 1 Agonist
TFLLRN
|
1 mg |
61530 |
| PAR - 1 Agonist, amide
TFLLRN-NH2
|
5 mg |
62937 |
| PAR - 1 Agonist, amide
TFLLRNPNDK-NH2
|
1 mg |
62936 |
| Protease - Activated Receptor - 2, PAR - 2 Agonist, amide
SLIGKV-NH2
|
1 mg
5 mg |
60217-1
60217-5 |
| PAR - 3 Agonist, amide
SFNGGP-NH2
|
1 mg |
62938 |
| PAR - 1 Agonist, amide
TFLLRNPNDK-NH2
|
1 mg
5 mg |
60218-1
60218-5 |
| Protease - Activated Receptor - 4, PAR - 4 Agonist, amide,
human
GYPGQV-NH2
|
1 mg |
60779 |
| Protease - Activated Receptor - 4, PAR - 4 Agonist, amide,
murine
GYPGKF-NH2
|
1 mg |
60778 |
| N - 10 Region of TRAP
DEIKYSEEVC
|
1 mg
5 mg |
60188-1
60188-5 |
Related Products and
Services:
RGD Peptides
Other Thrombin
related Peptides
MMP Antibodies, Assay
Kits and Substrates
References:
- Macfarlane, SR. et al. Pharmacol. Rev. 53, 245 (2001).
- Santulli, RJ. et al. PNAS 92, 9151 (1995).
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