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| Histones Peptides are GO™ – Acetylated & Methylated |
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The
core histones (H2A, H2B, H3 and H4) act as spools around which DNA winds.
Covalent modification on the amino terminal of the core histones through de/acetylation,
de/methylation and de/phosphorylation affect chromatin
structure and exquisitely regulate gene expression.1-3 Histone
hyperacetylation is correlated with increased transcription, whereas hypoacetylation
correlates with transcriptional repression.2
AnaSpec, the world’s largest provider of on-demand GO peptides is pleased
to announce the rapid expansion of our histone peptide selection. Histone
GOTM Peptides include sequences that are acetylated and di- or
tri-methylated. For sequences that are not found on this list, please request
a custom quotation here.
Histone H1 Peptides
H2A Peptides
Histone H3 Peptides
| Product |
Size |
Catalog
# |
| Histone H3
(1-20), N-Terminal NEW
ARTKQTARKSTGGKAPRKQL |
1 mg |
62753 |
| Histone H3
(1-21), N-Terminal
ARTKQTARKSTGGKAPRKQLA |
1 mg |
61701 |
| Histone H3
(1-21)-Cys NEW
ARTKQTARKSTGGKAPRKQLA-C |
1 mg |
63789 |
| Histone H3
(1-21)-GGK, Biotin-labeled
ARTKQTARKSTGGKAPRKQLA-GG-K(BIOTIN)-NH2 |
1 mg |
61702 |
| Histone H3
(1-21)-GGK, FAM-labeled NEW
ARTKQTARKSTGGKAPRKQLA-GG-K(FAM)-NH2 |
1 mg |
63824 |
| Histone H3
(1-25), amide
ARTKQTARKSTGGKAPRKQLATKAA-NH2 |
1 mg |
61703 |
| Histone H3
(15–39)
APRKQLATKAARKSAPATGGVKKPH |
1 mg |
61705 |
| Histone H3
(116–136), C116–136
KRVTIMPKDIQLARRIRGERA |
1 mg |
61704 |
| [Lys(Ac)14]-Histone
H3 (1-19), H3K14(Ac) NEW
ARTKQTARKSTGG-K(Ac)-APRKQL |
1 mg |
63682 |
| [Lys(Ac)9]-Histone
H3 (1-20), H3K9(Ac) NEW
ARTKQTAR-K(Ac)-STGGKAPRKQL |
1 mg |
63680 |
| [Lys(Ac)14]-Histone
H3 (9-19), H3K14(Ac) NEW
KSTGG-K(Ac)-APRKQ |
1 mg |
63681 |
| [Lys(Me2)4]-Histone
H3 (1-21), H3K4(Me2) NEW
ART-K(Me2)-QTARKSTGGKAPRKQLA |
1 mg |
63677 |
| [Lys(Me2)4]-Histone H3 (1 - 21), H3K4(Me2), FAM labeled NEW
ART-K(Me2)-QTARKSTGGKAPRKQLAGG-K(FAM)-NH2 |
1 mg |
63825 |
| [Lys(Me3)9]-Histone
H3 (1-24), H3K9(Me3) NEW
ARTKQTAR-K(Me3)-STGGKAPRKQLATKA |
0.5 mg |
63679 |
| [Lys(Me2)9]-Histone
H3 (1-24), H3K9(Me2), Biotin-labeled NEW
ARTKQTAR-K(Me2)-STGGKAPRKQLA-K(Biotin) |
1 mg |
63678 |
Histone H4 Peptides
| Product |
Size |
Catalog
# |
| Histone H4
(1-7), N-Terminal NEW
SGRGKGG |
1 mg |
62754 |
| Histone H4
(1-20), PRMT7 Substrate, M1 NEW
SGRGKGGKGLGKGGAKRHRK-NH2 |
1 mg |
62498 |
| Histone H4
(1-21), p300/CBP Substrate NEW
SGRGKGGKGLGKGGAKRHRKV |
1 mg |
62499 |
| Histone
H4 (1-21)-Lys(Biotin) NEW
Ac-SGRGKGGKGLGKGGAKRHRKVGG-K(Biotin) |
1 mg |
62555 |
| [Lys(Ac)5]-Histone
H4 (1-20), H4K5(Ac) NEW
SGRG-K(Ac)-GGKGLGKGGAKRHRK |
1 mg |
63683 |
| [Lys(Ac)8]-Histone
H4 (1-20), H4K8(Ac) NEW
SGRGKGG-K(Ac)-GLGKGGAKRHRK |
1 mg |
63684 |
| [Lys(Ac)12]-Histone
H4 (1-20), H4K12(Ac) NEW
SGRGKGGKGLG-K(Ac)-GGAKRHRK |
1 mg |
63685 |
| [Lys(Ac)16]-Histone
H4 (1-20), H4K16(Ac) NEW
SGRGKGGKGLGKGGA-K(Ac)-RHRK |
1 mg |
63687 |
| Histone
H4 –12, p300/CBP Substrate NEW
RGKGGKGLGKGA |
1 mg |
62500 |
| [Lys(Ac)16]-Histone
H4 (14-21), Mca-labeled, H4K16(Ac) (14-21), pepH4 - AcK16 NEW
Mca-GA-K(Ac)-RHRKV-NH2 |
1 mg |
63686 |
Related Products
AnaSpec is the sole provider
of the industry’s long wavelength HDAC assay kit, the SensoLyte 520 HDAC
Activity Assay Kit. We also provide unusual amino acid building blocks
such as Lys(Ac),
Lys(Me1-3), Arg(Me2)
, pSer
and pThr
for histone peptide synthesis.
References:
1. Jenuwein, T. and CD. Allis Science 293,
1074 (2001).
2. Sterner, DE. et al. Microbiol. Mol. Biol. Rev. 64,
435 (2000).
3. Lachner, M. et al. J. Cell Sci. 116,
2117 (2003).
Updated June 2, 2009
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