Zebrafish (Danio rerio) as an experimental model has gained widespread
use since the pioneering days of Dr. George Streisinger. In the year
1980, there were 18 publications, 72 in 1990, 540 in 2000 and 1159 in 2008.1
To date, there are more than 13,200 publications.2 In order to address
the growing needs of the research community for zebrafish specific antibodies,
peptides and other products, AnaSpec is pleased to announce the launching of
the Z-Fish™ product line.
Z-Fish™ antibodies are raised strictly from peptide antigens derived from zebrafish
protein sequences, i.e. 100% zebrafish sequence homology. Leveraging AnaSpec’s
expertise in peptide technology, the antigens used in raising these antibodies
include non-phosphorylated and phosphorylated peptides. The antibodies are purified
using proprietary purification methods.
The list of Z-Fish™ antibodies includes targets used in apoptosis and autophagy,
cell cycle control, cytoskeleton, glucose and energy metabolism, signal transduction,
and immunity research. Antibodies were verified in ELISA and in western blots,
lysates. Z-Fish™ antibodies are supplied in 150 ul sizes and are enough
for 15 mini gels.
Z-Fish™ cytoskeleton antibodies include anti-actin,
α-smooth muscle, anti-beta-actin,
raised with peptide antigens either from the C or N-terminus of the protein,
an actin related product. β-Catenin, a protein that bridges between cadherins
and actin and plays a central role in cell adhesion,can be phosphorylated by
GSK-3.3-6 One phosphorylated and two non-phosphorylated antibodies
are available for this protein.
For custom production of zebrafish antibodies, phosphorylated or non-phosphorylated,
please contact AnaSpec (email@example.com).
of Z-Fish™ antibodies
- Fish™ Embryonic Lysate (24 hpf) NEW
- Fish™ Embryonic Lysate (48 hpf) NEW
- Fish™ Embryonic Lysate (72 hpf) NEW
- Fish™ Lysate (5 dpf) NEW
Full listing of
- ZFIN; Retrieved Apr. 15, 2009 from http://nar.oxfordjournals.org/cgi/reprint/31/1/241.
- Highwire; Retrieved Apr. 15, 2009 from http://highwire.org.
- Dale, TC. Biochem. J. 329, 209 (1998).
- Sadot, E. et al. J. Cell Sci. 115, 2771 (2002).
- Giannini, A. et al. J. Biol. Chem. 275, 21883 (2000).
- Thilo, H. et al. J. Biol. Chem. 277, 2330 (2002).