From the maker of the world’s most sensitive MMP fluorimetric
assays kits comes the industry’s most comprehensive collection of anti-MMP zebrafish
(Z-Fish™) specific antibodies. AnaSpec, an integrated research solutions provider,
is pleased to complement our SensoLyte® MMP assay kits, GO™ (catalog)
MMP peptides, MMP recombinant proteins products, with a wide selection of Z-Fish™
(Table 1) as well as human (Table 2) specific MMP antibodies.
Matrix metalloproteinases (MMPs) are members of a family of
secreted or membrane-associated zinc endopeptidases involved in both normal
and diseased tissue remodeling. They are capable of degrading all kinds of extracellular
matrix (ECM) proteins, but also can process a number of bioactive molecules.
MMPs are key players in normal and pathological processes, including embryogenesis,
wound healing, inflammation, arthritis, and cancer.1-2
Table 1. Z-Fish™ specific anti-MMP antibodies.
| Product |
Size |
Cat# |
| Anti
- MMP - 2 (IN), Z-Fish™ NEW |
150 ul/15 mini-WB |
55111 |
| Anti
- MMP - 9 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55345 |
| Anti
- MMP - 11 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55113 |
| Anti
- MMP - 13 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55114 |
| Anti
- MMP - 14 - alpha (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55115 |
| Anti
- MMP - 14 - beta (CT), Z-Fish™ NEW |
150 ul/15 mini-WB |
55380 |
| Anti
- MMP - 14 - beta (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55116 |
| Anti
- MMP - 17 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55358 |
| Anti
- MMP - 18 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55403 |
| Anti
- MMP - 18 (IN), Z-Fish™ NEW |
150 ul/15 mini-WB |
55402 |
| Anti
- MMP - 24 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55346 |
| Anti
- MMP - 28 (hinge), Z-Fish™ NEW |
150 ul/15 mini-WB |
55405 |
 |
| Figure 5. IHC
of human inflammatory cells including lymphocytes and dendritic cells (formalin-fixed,
paraffin-embedded) probed with anti-MMP-9,
cat# 29579. This image shows the localization of the antibody as the
precipitated red signal, with a hematoxylin purple nuclear counterstain.
|
| |
 |
| Figure 6. IHC
of human malignant melanoma cells (formalin-fixed, paraffin-embedded) probed
with anti-MMP-13, cat#
54406. This image shows the localization of the antibody as the precipitated
red signal, with a hematoxylin purple nuclear counterstain. |
Table 2. Human specific anti-MMP antibodies.
| Product |
Size |
Cat
# |
| Anti-MMP-1
(hinge)
Collagenase-1
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB |
50 µg |
54403 |
| Anti-MMP-1
(NT)
Collagenase-1, Interstitial Collagenase
Host: rabbit polyclonal; Species Reactivity: human; Application:
ICC |
50 µg |
29574 |
| Anti-MMP-2
(CT)
matrix metallopeptidase 2
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB, IP |
50 µg |
29575 |
| Anti-MMP-3
(NT)
Stromelysin-1
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB, ICC |
50 µg |
29576 |
| Anti-MMP-7
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB, ICC |
50 µg |
29577 |
| Anti-MMP-8
(hinge)
Collagenase 2, Neutrophil Collagenase
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB, ICC |
50 µg |
29578 |
| Anti-human
MMP-9 (hinge)
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB |
50 µg |
54407 |
| Anti-MMP-9
(hinge-2)
Gelatinase B, Type V Collagenase
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB, ICC |
50 µg |
29579 |
| Anti-MMP-10
(hinge) (Stromelysin-2, Transin-2)
Host: rabbit polyclonal; Species Reactivity: human; Application:
ICC, Dot Blot |
50 µg |
29580 |
| Anti-MMP-13
(hinge)
Collagenase-3
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB, IHC |
50 µg |
54406 |
| Anti-MMP-16
(IN)
MT3-MMP
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB |
50 µg |
29581 |
| Anti-MMP-28
(IN)
Epilysin
Host: rabbit polyclonal; Species Reactivity: human; Application:
WB |
50 µg |
53379 |
Related Products:
Full
listing of Z-Fish™ antibodies
Z
- Fish™ Embryonic Lysate (24 hpf) NEW
Z
- Fish™ Embryonic Lysate (48 hpf) NEW
Z
- Fish™ Embryonic Lysate (72 hpf) NEW
Z
- Fish™ Lysate (5 dpf) NEW
Full listing
of antibodies
References:
1. Woessner, JF. Jr. and CJ. Taplin, J. Biol. Chem. 263, 16918
(1988).
2. Woessner, JF. Jr. FASEB. J. 5, 2145 (1991).
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