|
|
| Fluorescent Ca2+ Indicators – Premium Quality |
|
|
Calcium
plays a vital role in the regulation of cardiac contractility, growth and
gene expression; consequently, calcium measurement is critical in numerous
biological investigations. Fluorescent probes that show spectral responses
upon Ca2+ binding have enabled researchers to investigate changes
in intracellular free Ca2+ concentrations using techniques such
as fluorescence microscopy, flow cytometry, fluorescence spectroscopy. Most
of these fluorescent indicators are derivatives of BAPTA, chelators that incorporate
a photo-induced-electron transfer (PET) system responsive to calcium. Instruments,
such as FLIPR® and FlexStationTM have enabled high throughput measurement
of calcium for GPCR and ion channel research.
AnaSpec
is pleased to highlight a wide selection of fluorescent Ca2+ indicators.
These calcium indicators are of the highest quality and are cost-effective.
They include UV-excitable and visible light-excitable calcium indicators.
Among the UV-excitable calcium indicators, Fura-2 and Indo-1 are the
most commonly used. Fura-2 is excitation-ratioable while indo-1 is emission-ratioable.
While Fluo-3 and Rhod-2 are the most commonly used among the visible light-excitable
calcium indicators. Fluo-3 indicators are widely used in flow cytometry and
confocal laser-scanning microscopy. More recently, Fluo-3, AM has been extensively
used in cell-based HTS assays for functional GPCR assays. The long-wavelength
Ca2+ indicators, Rhod-2 and X-rhod-1, are valuable alternatives
to Fluo-3 for experiments in cells and tissues that have high autofluorescence.
To inquire about licensing opportunities for AnaSpec dyes, please email
service@anaspec.com.
UV-Excitable Calcium Indicators
| Product |
Size |
Catalog
# |
| Fura
– 2, AM |
1 mg |
84015 |
| Fura - 2, AM *UltraPure Grade* |
1 mg |
84016 |
| Fura - 2, AM *UltraPure Grade* *Bulk Packaging* |
50 mg |
84019 |
| Fura - 2, AM *UltraPure Grade*, 1 mM solution in anhydrous
DMSO |
1 mL |
84018 |
| Fura - 2, pentapotassium salt |
1 mg |
84011 |
| Fura - 2, pentasodium salt |
1 mg |
84012 |
| Fura - 2; AM *UltraPure Grade* *Small Package* |
50 µg x 20 |
84017 |
| Indo - 1, AM |
1 mg |
84006 |
| Indo - 1, AM *UltraPure Grade* |
1 mg |
84007 |
| Indo - 1, AM *UltraPure Grade* *Bulk packaging* |
50 mg |
84010 |
| Indo - 1, AM *UltraPure Grade*, 1 mM solution in anhydrous
DMSO |
1 mg |
84009 |
| Indo - 1, pentapotassium salt |
1 mg |
84000 |
| Indo - 1, pentasodium salt |
1 mg |
84001 |
| Indo - 1; AM *UltraPure Grade* *Small Package* |
50 µg x 20 |
84008 |
| Indo - 5F, AM |
1 mg |
84051 |
| Indo - 5F, pentapotassium salt |
1 mg |
84050 |
Visible Light-Excitable Calcium Indicators
| Product |
Size |
Catalog # |
| Fluo - 3, AM |
1 mg |
84024 |
| Fluo - 3, AM *UltraPure Grade* |
1 mg |
84025 |
| Fluo - 3, AM *UltraPure Grade* *Bulk Packaging* |
50 mg |
84028 |
| Fluo - 3, AM *UltraPure Grade*, 1 mM solution in anhydrous
DMSO |
1 mL |
84027 |
| Fluo - 3, pentaammonium salt |
1 mg |
84020 |
| Fluo - 3, pentapotassium salt |
1 mg |
84021 |
| Fluo - 3, pentasodium salt |
1 mg |
84022 |
| Fluo - 3; AM *UltraPure Grade* *Small Package* |
50 µg x 20 |
84026 |
| Fluo – 5F, pentapotassium salt |
1 mg |
84055 |
| Fluo
– 5F, AM |
1 mg |
84056 |
| Fluo
– 5N, pentapotassium salt |
1 mg |
84057 |
| Fluo – 5N, AM |
1 mg |
84058 |
| Rhod - 2, AM |
1 mg |
84034 |
| Rhod - 2, AM *UltraPure Grade* |
1 mg |
84035 |
| Rhod - 2, AM *UltraPure Grade* *Bulk Packaging* |
50 mg |
84038 |
| Rhod - 2, AM *UltraPure Grade*, 1 mM solution in anhydrous
DMSO |
1 mg |
84037 |
| Rhod - 2, tripotassium salt |
1 mg |
84030 |
| Rhod - 2, trisodium salt |
1 mg |
84031 |
| Rhod - 2; AM *UltraPure Grade* *Small Package* |
50 µg x 20 |
84036 |
| Rhod - 5F, AM |
1 mg |
84060 |
| Rhod - 5F, tripotassium salt |
1 mg |
84059 |
| Rhod - 5N, AM |
1 mg |
84062 |
| Rhod - 5N, tripotassium salt |
1 mg |
84061 |
| X - Rhod - 1, tripotassium salt |
1 mg |
84049 |
| X - Rhod - 1, AM |
1 mg |
84048 |
|
|
|
|
|
|
|
|
|
|
|
|
|
