390 MMP FRET Substrate 2 - 5 mg
- Cat.Number : AS-27079
- Manufacturer Ref. :
-
Availability :
In stock
Matrix Metalloproteinases (MMPs) are a large family of endopeptidases. Collectively, MMPs can degrade all kinds of extracellular matrix proteins, and can also process a number of bioactive molecules. They are known to be involved in the cleavage of cell surface receptors, the release of apoptotic ligands, and chemokine/cytokine inactivation. MMPs are also thought to play a major role in cell behaviors such as cell proliferation, migration (adhesion/dispersion), differentiation, angiogenesis, apoptosis, and host defense.
This peptide is a generic fluorogenic substrate for assaying MMPs. Abs/Em = 325/393 nm.
Specifications
| Chemistry | |
| Sequence one letter code |
|
|---|---|
| Sequence three letter code |
|
| Molecular Formula |
|
| Molecular Mass/ Weight |
|
| Properties | |
| Absorbance (nm) |
|
| Emission (nm) |
|
| Modification | |
| Conjugation type |
|
| Modification Name | |
| Conjugation |
|
| Quantity & Purity | |
| Purity |
|
| Storage & stability | |
| Form |
|
| Storage Conditions |
|
| Activity | |
| Application | |
| Biomarker Target | |
| Detection Method | |
| Research Area | |
| Sub-category Research Area | |
| Usage |
|
| Source | |
| Source / Species |
|
Downloads
You may also be interested in the following product(s)
SensoLyte® 520 Generic MMP Activity Kit Fluorimetric - 1 kit
References
Kinetic Analysis of Matrix Metalloproteinase Activity Using Fluorogenic Triple-Helical Substrates
Biochem . 2001 Apr 18 ; 40(19) 5795 | DOI : https://doi.org/10.1021/bi0101190
- JL. Lauer-Fields
- et al
Biochemical characterization of human collagenase-3
J Biol Chem . 1996 Jan 19 ; 271(3) 1544 | DOI : 10.1074/jbc.271.3.1544.
- V. Knauper
- et al
Design and characterization of a fluorogenic substrate selectively hydrolyzed by stromelysin 1 (matrix metalloproteinase-3).
J Biol Chem . 1994 Aug 19 ; 269 20952
- H. Nagase
- et al