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Assay Kits  >  MMP Assay Kits  >>  SensoLyte® 520 MMP Substrate Sampler Kit *Fluorimetric*

Product Name SensoLyte® 520 MMP Substrate Sampler Kit *Fluorimetric*
Size 1 kit
Catalog # 71170
US$ $627
Description

Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. They are involved in diseases such as cancer, arthritis, asthma, angiogenesis, alopecia and metastasis. They are also identified as drug-screening targets. SensoLyte® 520 MMP Substrate Sampler Kit contains a series of FRET peptide substrates for use as fluorogenic indicators to assay MMP protease activities. It provides the best solution for identifying a suitable fluorogenic substrate for a particular MMP assay. All the MMP substrates in the kit are also available in bulk packages.

Kit size: 16X 20 assays

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20°C
Product Citations Wirsching, H-G. et al. (2014). Thymosin beta 4 Gene Silencing Decreases Stemness and Invasiveness in Glioblastoma. Brain 137, 433. doi: 10.1093/brain/awt333.
Iwakura, Y. et al. (2011). Dopamine-dependent ectodomain shedding and release of epidermal growth factor in developing straitum: target-derived neurotrophic signaling (Part 2). J Neurochem 10.1111/j.1471-4159.2011.07295.x.
Allington, TM. et al. (2009). Activated Abl kinase inhibits oncogenic transforming growth factor-β signaling and tumorigenesis in mammary tumors. FASEB J 23, 4231.
Schaal, R. et al. (2007). Systematic identification of substrates for profiling of secreted proteases from Aspergillus species. J Microbio Meth 71, 93.
White, AR. et al. (2006). Degradation of the Alzheimer Disease amyloid β-peptide by metal-dependent upregulation of metalloprotease activity. J Biol Chem 281, 17670.
     
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