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Fluorescent Dyes  >  Fluorescent Physiological and Neurological Indicators  >>  Oxonol VI

Product Name Oxonol VI
[Bis - (3 - propyl - 5 - oxoisoxazol - 4 - yl)pentamethine oxonol]
Size 100 mg
Catalog # AS-84704
US$ $159
Description

Oxonol VI is used as an optical indicator for membrane potentials in lipid vesicles. Oxonol VI is a sensitive slow-response membrane potential probe whose magnitude of optical response is much larger than that of faster response probes (Oxonol V). The fluorescence of Oxonol VI decreases upon membrane hyperpolarization. In general, slow response probes are suitable for detecting changes in average membrane potentials of nonexcitable cells caused by respiratory activity, ion-channel permeability, drug binding and other factors.

Detailed Information Datasheet
Material Safety Data Sheets (MSDS)
Storage -20C desiccated and protected from light
References 1. Cheng Z, et al. (2004). Am J Physiol Regul Integr Comp Physiol 286, R625-33.
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4. Suksaweang S, et al. (2004). Dev Biol 266, 109-22.
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7. Zhang X and Kirsch LE (2004). Pharm Dev Technol 9, 219-27.
8. Hefnawy MA and Abou-Zeid AM (2003). Acta Microbiol Pol 52, 53-64.
9. Jordan MB, et al. (2003). Blood 101, 594-601.
10. Bianchi L, et al. (2003). J Biol Chem 278, 12415-24.
11. deAzevedo LC, et al. (2003). J Neurobiol 55, 288-98.
12. Ramani K and Balasubramanian SV (2003). Biochim Biophys Acta 1618, 67-78.
Molecular Weight 316.352
Molecular Formula C17H20N2O4
Spectral Properties Abs/Em = 599/634 nm
Solvent System DMSO
Product Citations Mennerick, S. et al. (2010). Diverse Voltage-Sensitive Dyes Modulate GABAAReceptor Function. J Neurosci 30, 2871.
     
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