IMG-EN-AS-60430-1-01.jpg
Peptides

PEP1 - 1 mg

$357.00
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  • Cat.Number : AS-60430-1
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    In stock

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This synthetic peptide mimics wild-type AH (amphipathic helix) and inhibits membrane association of NS5A, hence impairing HCV replication.

Specifications

Chemistry
Sequence one letter code
  • SGSWLRDVWDWICTVLTDFKTWLQSKLDYKD-NH2
Sequence three letter code
  • Ser-Gly-Ser-Trp-Leu-Arg-Asp-Val-Trp-Asp-Trp-Ile-Cys-Thr-Val-Leu-Thr-Asp-Phe-Lys-Thr-Trp-Leu-Gln-Ser-Lys-Leu-Asp-Tyr-Lys-Asp-NH2
Molecular Formula
  • C177H259N43O49S
Molecular Mass/ Weight
  • 3805.5
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • HCV

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References

Amphipathic Helix-Dependent Localization of NS5A Mediates Hepatitis C Virus RNA Replication

J Virol . 2003 May 01 ; 77(10) 6055 | DOI : 10.1128/JVI.77.10.6055-6061.2003

  • M. Elazar
  • et al