Login
Existing Account

Please login first to complete purchase/ quotation request, view custom order reports, or create favorites list.

Customer ID:
Password:
Stay Logged In


Forgot your Customer ID or Password?
New Account

Don't have an account with us yet? Please set up an account to place order or obtain customer services.

Peptides  >  Angiotensins and Related Peptides  >>  Biotin-LC-Angiotensin II

Product Name Biotin - LC - Angiotensin II
Biotin - LC - DRVYIHPF
Size 1 mg
Catalog # AS-60276-1
US$ $66
Purity % Peak Area By HPLC ≥ 95%
Description

This octapeptide Angiotensin II, DRVYIHPF, is biotinylated on the N-terminus via an LC (long chain, also known as 6-Aminohexanoyl, 6-Aminocaproyl or Ahx) linker. It can be used in ELISA assay. Angiotensin II (Ang II) exerts a wide range of effects on the cardiovascular system. It is also implicated in the regulation of cell proliferation, fibrosis and apoptosis. Ang II is formed by cleavage of Ang I by the angiotensin-converting enzyme (ACE) or chymases. Human heart chymase, a chymotrypsin-like serine proteinase, hydrolyzes the Phe8-His9 bond to yield the octapeptide hormone angiotensin II and His-Leu.

Storage -20C
References 1, Cobb, C. et al. Gen Comp Endocrinol 127, 8 (2002)
2, Lundequist, A. et al. J Biol Chem 279, 32339 (2004)
3, Kinoshita, A. et al. J Biol Chem 266, 19192 (1991)
4, Spyroulias, G. et al. Eur J Biochem 270, 2163 (2003).
Molecular Weight 1385.7
Sequence
(One-Letter Code)
Biotin-LC-DRVYIHPF
Sequence
(Three-Letter Code)
Biotin - LC - Asp - Arg - Val - Tyr - Ile - His - Pro - Phe - OH
Product Citations Young, SH. & E. Rozengurt (2006). Qdot nanocrystal conjugates conjugated to bombesin or ANG II label the cognate G protein-coupled receptor in living cells. Am J Physiol-Cell Physiol 290, C728. doi: 10.1152/ajpcell.00310.2005.
     
  < Back