IMG-EN-AS-22464-01.jpg
Peptides

Neuropeptide Y, human, rat

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  • Cat.Number : AS-22464
  • Availability :
    In production

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Neuropeptide Y (NPY) is a 36aa neuropeptide involved in food intake, fat metabolism, stress and pain reduction, and vasodilation

Specifications

Chemistry
Sequence one letter code
  • YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY-NH2
Sequence three letter code
  • H-Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr-NH2
CAS registry number
  • 90880-35-6
Molecular Formula
  • C189H285N55O57S
Molecular Mass/ Weight
  • 4272
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Heterobivalent dual-target probe for targeting GRP and Y1 receptors on tumor cells.

Bioorg Med Chem Lett . 2012 Dec 05 ; 23(3) 687 | DOI : 10.1016/j.bmcl.2012.11.110.

  • A. Shrivastava

ICV NPY Y1 receptor agonist but not Y5 agonist induces torpor-like hypothermia in cold-acclimated Siberian hamsters.

Am J Physiol Regulatory Integrative Comp Physiol . 2007 Mar 01 ; 292(6) R2299 | DOI : 10.1152/ajpregu.00790.2006

  • KM. Pelz

Selective activation of central NPY Y1 vs. Y5 receptor elicits hyperinsulinemia via distinct mechanisms.

Am J Physiol Endocrinol Metab . 2004 Jun 08 ; 287(4) E706 | DOI : 10.1152/ajpendo.00530.2003.

  • J. Gao

Substance P and NPY differentially potentiate ATP and adrenergic stimulated vasopressin and oxytocin release.

Am J Physiol Regul Integr Comp Physiol . 2001 Jan 01 ; 280(1) R69 | DOI : 10.1152/ajpregu.2001.280.1.R69

  • JR. Kapoor
  • CD. Sladek

References

Cloning, characterization, and DNA sequence of a human cDNA encoding neuropeptide tyrosine

PNAS . 1984 Jul 01 ; 81(14) 4577 | DOI : https://doi.org/10.1073/pnas.81.14.4577

  • C. Minth
  • et al