IMG-EN-AS-60772-01.jpg
Peptides

Apamin - 0.5 mg

$147.00
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  • Cat.Number : AS-60772
  • Availability :
    In production

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A 18-amino acid peptide from bee venom, a selective blocker of calcium activated potassium channels.

Specifications

Chemistry
Sequence one letter code
  • CNCKAPETALCARRCQQH-NH2 (Disulfide bridge: 1-11; 3-15)
Sequence three letter code
  • H-Cys-Asn-Cys-Lys-Ala-Pro-Glu-Thr-Ala-Leu-Cys-Ala-Arg-Arg-Cys-Gln-Gln-His-NH2 (Disulfide bridge: 1-11, 3-15)
CAS registry number
  • 24345-16-2
Molecular Formula
  • C79H131N31O24S4
Molecular Mass/ Weight
  • 2027.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • honey bee

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References

Apamin, a blocker of the calcium-activated potassium channel, induces neurodegeneration of Purkinje cells exclusively

Brain Res . 1997 Dec 19 ; 778(2) 405 | DOI : https://doi.org/10.1016/S0006-8993(97)01165-7

  • C. Mourre
  • et al

Bee and Wasp Venoms

Science . 1972 Jul 28 ; 117 314 | DOI : https://www.jstor.org/stable/1734340

  • E. Habermann