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Peptides

ω-Conotoxin GVIA

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  • Cat.Number : AS-22926
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This peptide is a neurotoxin that blocks N-type calcium channels.

Specifications

Chemistry
Sequence one letter code
  • CKS(Hyp)GSSCS(Hyp)TSYNCCRSCN(Hyp)YTKRCY-NH2
Sequence three letter code
  • H-Cys-Lys-Ser-Hyp-Gly-Ser-Ser-Cys-Ser-Hyp-Thr-Ser-Tyr-Asn-Cys-Cys-Arg-Ser-Cys-Asn-Hyp-Tyr-Thr-Lys-Arg-Cys-Tyr-NH2 (Disulfide bridges: 1-16, 8-19, 15-26)
CAS registry number
  • 106375-28-4
Molecular Formula
  • C218H358N62O65S3
Molecular Mass/ Weight
  • 3037.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Snail

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References

Effects of site-specific acetylation on .omega.-conotoxin GVIA binding and function

Biochem . 1993 Apr 01 ; 32(13) 3255 | DOI : https://doi.org/10.1021/bi00064a007

  • RA. Lampe
  • et al

Neuronal calcium channel inhibitors. Synthesis of omega-conotoxin GVIA and effects on 45Ca uptake by synaptosomes.

JBC . 1987 Jan 25 ; 262(3) 1194 | DOI : https://doi.org/10.1016/S0021-9258(19)75770-6

  • J. Rivier
  • et al