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Peptides

Melan-A, MART-1 (27-35) - 1 mg

$147.00
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  • Cat.Number : AS-60608
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Melan-A is a melanocyte differentiation antigen recognized by cytotoxic T lymphocytes. This sequence is a naturally presented Melan-A/MART-1 nonamer peptide. The Melan-A/MART-1 gene is expressed by normal melanocytes, as well as by most fresh melanoma samples and melanoma cell lines. This peptide appears to be a very common immunogenic epitope for HLA-A2-restricted melanoma-specific tumor-infiltrating lymphocytes (TIL) and may be useful for the development of immunotherapeutic strategies.

Specifications

Chemistry
Sequence one letter code
  • AAGIGILTV
Sequence three letter code
  • H-Ala-Ala-Gly-Ile-Gly-Ile-Leu-Thr-Val-OH
CAS registry number
  • 156251-11-5
Molecular Formula
  • C37H67N9O11
Molecular Mass/ Weight
  • 814.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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References

Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes.

J Exp Med . 1994 Jul 01 ; 180(1) 347 | DOI : https://doi.org/10.1084/jem.180.1.347

  • Y. Kawakami
  • et al

Overlapping peptides of melanocyte differentiation antigen melan-A/MART-1 recognized by autologous cytolytic T lymphocytes in association with HLA-B45.1 and HLA-A2.1

Int J Cancer . 1998 Jan 30 ; 75(3) 451 | DOI : https://doi.org/10.1002/(SICI)1097-0215(19980130

  • J. Schneider
  • et al