IMG-EN-AS-60193-1-01.jpg
Peptides

OVA (257-264) Peptide Fragment

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  • Cat.Number : AS-60193-1
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    In stock

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This is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.

Specifications

Chemistry
Sequence one letter code
  • SIINFEKL
Sequence three letter code
  • H-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu-OH
CAS registry number
  • 138831-86-4
Molecular Formula
  • C45H74N10O13
Molecular Mass/ Weight
  • 963.2
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • chicken

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Citations

Murine liver-resident group 1 innate lymphoid cells regulate optimal priming of anti-viral CD8+ T cells

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Profound Impairment of Adaptive Immune Responses by Alkylating Chemotherapy

J Immunol. . 2013 Jun 15 ; 190(12) 6259 | DOI : 10.4049/jimmunol.1203539

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Programmed death-1 blockade enhances the antitumor effects of peptide vaccine-induced peptide-specific cytotoxic T lymphocytes

Intl J Oncol . 2014 Oct 30 ; 46(1) 28 | DOI : 10.3892/ijo.2014.2737

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A peptide antigen derived from EGFR T790M is immunogenic in non‑small cell lung cancer

Int J Oncol. . 2014 Dec 01 ; 46(2) 497 | DOI : 10.3892/ijo.2014.2787

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The DNA damage response induces antigen presenting cell-like functions in fibroblasts

Eur J Immunol . 2014 Feb 16 ; 44(4) 1108 | DOI : 10.1002/eji.201343781

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Discs Large Homolog 1 Splice Variants Regulate p38-Dependent and -Independent Effector Functions in CD8+ T Cells.

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The p50 subunit of NF-κB orchestrates dendritic cell lifespan and activation of adaptive immunity

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Lymph node fibroblastic reticular cells directly present peripheral tissue antigen under steady-state and inflammatory conditions

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Blood . 2010 Feb 04 ; 115(5) 1088 | DOI : 10.1182/blood-2009-05-223198

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DC-expressed MHC class I single-chain trimer-based vaccines prime cytotoxic T lymphocytes against exogenous but not endogenous antigens

Cell Immunol . 2010 Feb 10 ; 262(2) 141 | DOI : https://doi.org/10.1016/j.cellimm.2010.02.006

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Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

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Ly6Clow monocytes differentiate into dendritic cells and cross-tolerize T cells through PDL-1

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MHC class I/peptide transfer between dendritic cells overcome poor cross-presentation by monocyte-derived APCs that engulf dying cells

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Puromycin-Sensitive Aminopeptidase Limits MHC Class I Presentation in Dendritic Cells but Does Not Affect CD8 T Cell Responses during Viral Infections

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  • CF. Towne

Chaperone-rich cell lysate embedded with BCR-ABL peptide demonstrates enhanced anti-tumor activity against a murine BCR-ABL positive leukemia

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The IL-15/IL-15Ra on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells

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J Immunol . 2006 Feb 15 ; 176(4) 2299 | DOI : https://doi.org/10.4049/jimmunol.176.4.2299

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Nectin-like Protein 2 Defines a Subset of T-cell Zone Dendritic Cells and Is a Ligand for Class-I-restricted T-cell-associated Molecule

J Biol Chem . 2005 Mar 21 ; 280(23) 21955 | DOI : 10.1074/jbc.M502095200

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A Role for a Novel Luminal Endoplasmic Reticulum Aminopeptidase in Final Trimming of 26 S Proteasome-generated Major Histocompatability Complex Class I Antigenic Peptides

J Biol Chem . 2001 May 23 ; 276(32) 30050 | DOI : 10.1074/jbc.M103177200

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26 S proteasome-mediated production of an authentic major histocompatibility class I-restricted epitope from an intact protein substrate

J Biol Chem . 1999 Jul 30 ; 274(31) 21963 | DOI : 10.1074/jbc.274.31.21963

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Production of a specific major histocompatibility complex class I-restricted epitope by ubiquitin-dependent degradation of modified ovalbumin in lymphocyte lysate

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SIGN-R1+MHC II+ cells of the splenic marginal zone—a novel type of resident dendritic cells

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Dectin-1-triggered Recruitment of Light Chain 3 Protein to Phagosomes Facilitates Major Histocompatibility Complex Class II Presentation of Fungal-derived Antigens

J Biol Chem . 2012 Aug 17 ; 287(41) 34149 | DOI : 10.1074/jbc.M112.382812

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Targeting NKT cells and PD-L1 pathway results in augmented anti-tumor responses in a melanoma model

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Memory CD8+ T cells require CD28 costimulation.

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Analysis of the Role of Bleomycin Hydrolase in Antigen Presentation and the Generation of CD8 T Cell Responses.

J Immunol . 2007 Jun 01 ; 178(11) 6923 | DOI : 10.4049/jimmunol.178.11.6923

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References

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