Pancreastatin (PST), originally isolated from porcine pancreas, is a 49-amino acid peptide with a C-terminal glycine amide. PST and chromostatin are chromogranin A (CGA)-derived peptides. PST has a general inhibitory effect on secretion in many exocrine and endocrine systems. It has been associated with a glucose and lipid metabolism in the liver and adipose tissue.
Ref: Gonzalez-Yanes, K. et al. Cell Signal. 13, 43 (2001); Santos-Alvarez et al. Arch. Biochem. Biophys. 378, 151 (2000); Jensen, T. et al. Scand J. Gastroenterol. 29, 376 (1994); Ahren, B. Eur. J. Pharmacol. 126, 97 (1986).