IMG-EN-AS-60789-01.jpg
Peptides

Phytochelatin 4, PC4 - 1 mg

$198.00
Check your price
  • Cat.Number : AS-60789
  • Availability :
    In stock

Alternative choices

Quantity

Add to wishlist Bulk Quote

A glutathione-derived heavy metal-detoxifying peptide of higher plants consisting of 4 units of gGlu-Cys.

Specifications

Chemistry
Sequence one letter code
  • (γE-C)4-G
Sequence three letter code
  • H-γ-Glu-Cys-γ-Glu-Cys-γ-Glu-Cys-γ-Glu-Cys-Gly-OH
Molecular Formula
  • C34H53N9O18S4
Molecular Mass/ Weight
  • 1004.1
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Plants

Downloads

You may also be interested in the following product(s)

IMG-EN-AS-60791-01.jpg

Phytochelatin 2, PC2 - 1 mg

Cat.Number : AS-60791
$164.00 Excl. Tax
IMG-EN-AS-60790-01.jpg

Phytochelatin 3, PC3 - 1 mg

Cat.Number : AS-60790
$169.00 Excl. Tax
IMG-EN-AS-61190-01.jpg

Phytochelatin 5, PC5 - 1 mg

Cat.Number : AS-61190
$182.00 Excl. Tax

Citations

Thiol compounds induction kinetics in marine phytoplankton during and after mercury exposure.

J Haz Mat . 2012 Mar 20 ; 217-218 271 | DOI : 10.1016/j.jhazmat.2012.03.024

  • Y. Wu
  • W-X. Wang

Complexation of Hg with phytochelatins is important for plant Hg tolerance.

Plant Cell Environ . 2011 Mar 15 ; 34(5) 778 | DOI : 10.1111/j.1365-3040.2011.02281.x

  • S. Carrasco-Gil

Fission yeast HMT1 lowers seed cadmium through phytochelatin-dependent vacuolar sequestration in Arabidopsis.

Plant Physiol . 2012 Feb 07 ; 158(4) 1779 | DOI : 10.1104/pp.111.192872

  • J. Huang

Microbial synthesis of CdS nanocrystals in genetically engineered E. coli.

Angewandte Chem Int Ed . 2008 Jun 20 ; 47(28) 5186 | DOI : 10.1002/anie.200705806

  • SH. Kang

Exploiting plants for glutathione (GSH) production: uncoupling GSH synthesis from cellular controls results in unprecedented GSH accumulation.

Plant Biotechnol J . 2010 Mar 11 ; 8(7) 807 | DOI : 10.1111/j.1467-7652.2010.00510.x

  • V. Liedschulte

Towards an understanding of the function of the phytochelatin synthase of Schistosoma mansoni.

PLoS Neglected Tropical Dis . 2013 Jan 31 ; 7(1) e2037 | DOI : 10.1371/journal.pntd.0002037

  • C. Rigouin

Role of metal mixtures (Ca, Cu and Pb) on Cd bioaccumulation and phytochelatin production by Chlamydomonas reinhardtii.

Environ Pollution . 2013 May 03 ; 179 33 | DOI : 10.1016/j.envpol.2013.03.047

  • P. Abboud
  • KJ. Wilkinson

Reduced translocation of cadmium from roots is associated with increased production of phytochelatins and their precursors.

J Plant Physiol . 2012 Aug 22 ; 169(18) 1821 | DOI : 10.1016/j.jplph.2012.07.011

  • MF. Akhter

Understanding of thiol-induced etching of luminescent gold nanoclusters.

RSC Adv . 2014 Jun 03 ; 4 26050 | DOI : 10.1039/C4RA02111H

  • C-Y. Ke

The influence of pH on algal cell membrane permeability and its implications for the uptake of lipophilic metal complexes.

J Phycol . 2012 Mar 19 ; 48(2) 293 | DOI : 10.1111/j.1529-8817.2012.01126.x

  • M. Lavoie

Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassica napus. A role for thiol-peptides in the long-distance transport of cadmium and the effect of cadmium on iron translocation.

Plant J. . 2008 Jan 16 ; 54(2) 249 | DOI : 10.1111/j.1365-313X.2008.03410.x

  • DG. Mendoza-Cozatl

Predicting copper toxicity with its intracellular or subcellular concentration and the thiol synthesis in a marine diatom.

Environ. Sci. Technol. . 2007 Mar 01 ; 41(5) 1777 | DOI : 10.1021/es0613963

  • AJ. Miao
  • W-X. Wang

SEC ICP MS and CZE ICP MS investigation of medium and high molecular weight complexes formed by cadmium ions with phytochelatins.

Anal Bioanal Chem. . 2013 Mar 23 ; 405(14) 4667 | DOI : 10.1007/s00216-013-6868-3

  • A. Miszczak

Cytokinin Determines Thiol-Mediated Arsenic Tolerance and Accumulation.

Plant Physiol. . 2016 Apr 18 ; 171(2) 1418 | DOI : 10.1104/pp.16.00372

  • T. Mohan

Characterization of the phytochelatin synthase from the human parasitic nematode Ancylostoma ceylanicum.

Mol Biochem Parasitol . 2013 Jul 31 ; 191(1) | DOI : 10.1016/j.molbiopara.2013.07.003

  • C. Rigouin

Selective extraction of thiol-containing peptides in seawater using Tween 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence.

J Chromatogr A . 2011 Dec 06 ; 1220 162 | DOI : 10.1016/j.chroma.2011.11.057

  • C-C. Shen

Characterization of Hg-phytochelatins complexes in vines (Vitis vinifera cv Malbec) as defense mechanism against metal stress.

BioMetals . 2014 Apr 09 ; 27(3) 591 | DOI : 10.1007/s10534-014-9732-9

  • AA. Spisso

Cadmium in three marine phytoplankton: accumulation, subcellular fate and thiol induction.

Aquatic Toxicol . 2009 Aug 25 ; 95(5) 99 | DOI : 10.1016/j.aquatox.2009.08.006

  • M-J. Wang,
  • W-X. Wang

Responses of non-protein thiols to Cd exposure in Cd hyperaccumulator Arabis paniculata Franch.

Environ. Exp. Botany . 2009 May 01 ; 66(2) 242 | DOI : https://doi.org/10.1016/j.envexpbot.2009.03.003

  • X. Zeng

Lead accumulation and synthesis of non-protein thiolic peptides in selected clones of Melilotus alba and Melilotus officinalis.

Environ Exp Botany . 2012 May 01 ; 78 18 | DOI : 10.1016/j.envexpbot.2011.12.016

  • R. Fernández

Effects of Zn on plant tolerance and non-protein thiol accumulation in Zn hyperaccumulator Arabis paniculata Franch.

Environ Exp Botany . 2011 Feb 01 ; 70(2-3) 227 | DOI : 10.1016/j.envexpbot.2010.09.009

  • X-W. Zeng

Identification of in vivo nitrosylated phytochelatins in Arabidopsis thaliana cells by liquid chromatography-direct electrospray-linear ion trap-mass spectrometry.

J Chromatog . 2010 Feb 12 ; 1217(25) 4120 | DOI : 10.1016/j.chroma.2010.02.013

  • L. Elviri

Separation and quantification of monothiols and phytochelatins from a wide variety of cell cultures and tissues of trees and other plants using high performance liquid chromatography.

J. Chromatogr. A . 2008 Aug 13 ; 1207(1-2) 72 | DOI : 10.1016/j.chroma.2008.08.023

  • R. Minocha

Effect of cadmium on selected physiological and morphological parameters in metallicolous and non-metallicolous populations of Echium vulgare L.

Ecotoxicol Environ Safety . 2014 Apr 15 ; 104 332 | DOI : 10.1016/j.ecoenv.2014.03.019

  • S. Dresler

Analysis of Plant Pb Tolerance at Realistic Submicromolar Concentrations Demonstrates the Role of Phytochelatin Synthesis for Pb Detoxification

Environ Sci Technol . 2014 May 28 ; 48 7552 | DOI : 10.1021/es405234p

  • S. Fischer

Analysis of phytochelatin complexes in the lead tolerant vetiver grass [Vetiveria zizanioides (L.)] using liquid chromatography and mass spectrometry.

Environ. Pollut. . 2009 Mar 17 ; 157(7) 2173 | DOI : 10.1016/j.envpol.2009.02.014

  • SS. Andra

S-Nitrosophytochelatins: Investigation of the Bioactivity of an Oligopeptide Nitric Oxide Delivery System

Biomacromol . 2011 Apr 11 ; 12(6) 2103 | DOI : 10.1021/bm200159h

  • L. Heikal

Biochemical and physiological changes in jack bean under mycorrhizal symbiosis growing in soil with increasing Cu concentrations.

Environ Exp Botany . 2010 Apr 01 ; 68(2) 198 | DOI : 10.1016/j.envexpbot.2009.11.009

  • SAL. Andrade

Determination and characterization of cysteine, glutathione and phytochelatins (PC 2–6) in Lolium perenne L. exposed to Cd stress under ambient and elevated carbon dioxide using HPLC with fluorescence detection.

J Chromatogr B Analyt Technol Biomed Life Sci. . 2011 Apr 22 ; 879(20) 1717 | DOI : 10.1016/j.jchromb.2011.04.016

  • XH. Ju

Copper-induced synthesis of ascorbate, glutathione and phytochelatins in the marine alga Ulva compressa(Chlorophyta).

Plant Physiol Biochem . 2011 Oct 11 ; 51 102 | DOI : 10.1016/j.plaphy.2011.10.007

  • M. Mellado

References

Phytochelatins and related peptides. Structure, biosynthesis, and function

Plant Physiol . 1995 Dec 01 ; 109(4) 1141 | DOI : 10.1104/pp.109.4.1141

  • WE. Rauser
  • et al

Phytochelatins: The Principal Heavy-Metal Complexing Peptides of Higher Plants

Science . 1985 Nov 08 ; 230(4726) 674 | DOI : 10.1126/science.230.4726.674

  • E. Grill
  • et al