IMG-EN-AS-60515-1-01.jpg
Peptides

Glycogen Synthase (1-10) [PLSRTLSVSS-NH2], 5-FAM labeled - 1 mg

$303.00
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  • Cat.Number : AS-60515-1
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    In stock

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The native peptide, PLSRTLSVSS-NH2, is a synthetic substrate for Ca2+-calmodulin-dependent protein kinase II (Km = 7.5 µM). Maximal activation of the decapeptide substrate phosphorylation requires the presence of Ca2+ and calmodulin and is dependent on Ca2+ concentration.

Specifications

Chemistry
Sequence one letter code
  • 5-FAM-PLSRTLSVSS-NH2
Sequence three letter code
  • 5-FAM-Pro-Leu-Ser-Arg-Thr-Leu-Ser-Val-Ser-Ser-NH2
Molecular Formula
  • C65H90N14O21
Molecular Mass/ Weight
  • 1403.5
Properties
Absorbance (nm)
  • 494
Emission (nm)
  • 521
Modification
Conjugation type
  • Fluorescent dyes
Modification Name
Conjugation
  • Conjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C Protected from light
Activity
Application
Biomarker Target
Detection Method
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • guinea pig, rabbit

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References

Agonist stimulation of Na+/K+/Cl- cotransport in rat glomerular mesangial cells. Evidence for protein kinase C-dependent and Ca2+/calmodulin-dependent pathways

JBC . 1990 Oct 15 ; 265(29) 17613 | DOI : https://doi.org/10.1016/S0021-9258(18)38208-5

  • T. Homma
  • et al

Calmodulin and calmodulin-dependent kinase II mediate neuronal cell death induced by depolarization

Brain Res . 2003 Feb 01 ; 962(1-2) 41 | DOI : https://doi.org/10.1016/S0006-8993(02)03932-X

  • H. Takano
  • et al