Peptides

Cholecystokinin (26-33), CCK8, Sulfated CCK-8 - 1 mg

$242.00
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  • Cat.Number : AS-20741
  • Availability :
    In stock

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C-terminal sulfated and amidated octapeptide Cholecystokinin (sulfated CCK-8) has the full biological action of the full-length 33-amino acid long Cholecystokinin (CCK). CCK acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.

Specifications

Chemistry
Sequence one letter code
  • D-Y(SO3H)-MGWMDF-NH2
Sequence three letter code
  • H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
CAS registry number
  • 25126-32-3
Molecular Formula
  • C49H62N10O16S3
Molecular Mass/ Weight
  • 1143.3
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat, pig

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References

Met-195 of the cholecystokinin-A receptor interacts with the sulfated tyrosine of cholecystokinin and is crucial for receptor transition to high affinity state.

J Biol Chem. . 1998 Jun 01 ; 273(23) 14380 | DOI : 10.1074/jbc.273.23.14380

  • V. Gigoux
  • et al