Peptides

Fibrinogen Binding Inhibitor Peptide - 1 mg

  • Cat.Number : AS-60700
  • Availability :
    In stock

Quantity

The fibrinogen binding inhibitor peptide is important for platelet aggregation. The sequence is derived from the carboxy terminus of the gamma chain of fibrinogen (residues 400-401). This is considered one of the common ligands for glycoprotein (GPIIb-IIIa) recognition and binding.

Specifications

Chemistry
Sequence one letter code
  • HHLGGAKQAGDV
Sequence three letter code
  • H-His-His-Leu-Gly-Gly-Ala-Lys-Gln-Ala-Gly-Asp-Val-OH
CAS registry number
  • 89105-94-2
Molecular Formula
  • C50H80N18O16
Molecular Mass/ Weight
  • 1189.4
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • human

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Citations

Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow.

Blood . 2010 Oct 29 ; 117(2) 651 | DOI : http://dx.doi.org/10.1182/blood-2010-01-262683

  • J. Cosemans

References

Role of fibrinogen alpha and gamma chain sites in platelet aggregation

Proc. Natl. Acad. Sci. . 1992 Nov 15 ; 89(22) 10729 | DOI : https://doi.org/10.1073/pnas.89.22.10729

  • DH. Farrell
  • et al