IMG-EN-AS-22945-01.jpg
Peptides

GRGDSP Peptide

$40.00
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  • Cat.Number : AS-22945
  • Availability :
    In production

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An inhibitor of cell attachment to salmosin and vitronectin.

Specifications

Chemistry
Sequence one letter code
  • GRGDSP
Sequence three letter code
  • H-Gly-Arg-Gly-Asp-Ser-Pro-OH
Molecular Formula
  • C22H37N9O10
Molecular Mass/ Weight
  • 587.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • synthetic

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Citations

Occurrence of oligosialic acids on integrin α5subunit and their involvement in cell adhesion to fibronectin.

J Biol Chem . 2001 Jun 19 ; 276 33657 | DOI : 10.1074/jbc.M011100200

  • S. Nadanaka

Development of pre-implantation porcine blastocysts cultured within alginate hydrogel systems either supplemented with secreted phosphoprotein 1 or conjugated with Arg-Gly-Asp Peptide.

Reprod Fertil Dev. . 2017 Nov 01 ; 29(12) 2345 | DOI : 10.1071/RD16366

  • T. Laughlin

TGF-β1-induced chondrogenesis of bone marrow mesenchymal stem cells is promoted by low-intensity pulsed ultrasound through the integrin-mTOR signaling pathway.

Stem Cell Res Ther . 2017 Dec 13 ; 8(1) 281 | DOI : 10.1186/s13287-017-0733-9

  • P. Xia

Branched-chain amino acids regulate insulin-like growth factor-binding protein 1 (IGFBP1) production by decidua and influence trophoblast migration through IGFBP1.

Mol Hum Reprod. . 2016 May 18 ; 22(8) 890 | DOI : https://doi.org/10.1093/molehr/gaw032

  • K. Tanaka

Marrow‐derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness.

Biotechnol Bioeng. . 2011 Jan 15 ; 108(5) 1181 | DOI : 10.1002/bit.23027.

  • SR. Peyton

Thy-1-integrin alphavbeta5 interactions inhibit lung fibroblast contraction-induced latent TGF-beta1 activation and myofibroblast differentiation. 

J Biol Chem  . 2010 May 12 ; 285(29) 22382 | DOI : 10.1074/jbc.M110.126227.

  • Y. Zhou

Integrin αIIbβ3 Activation in Chinese Hamster Ovary Cells and Platelets Increases Clustering Rather than Affinity. 

J Biol Chem  . 2010 Jan 15 ; 285(3) 1841 | DOI : 10.1074/jbc.M109.057349

  • T. Bunch

Induction of glioma cell migration by vitronectin in human serum and cerebrospinal fluid

J Neurosurg . 2007 Sep 01 ; 107(3) 578 | DOI : 10.3171/JNS-07/09/0578

  • Y. Fukushima

Cell-matrix entanglement and mechanical anchorage of fibroblasts in three-dimensional collagen matrices. 

Mol Biol Cell  . 2005 Nov 01 ; 16(11) 5070 | DOI : 10.1091/mbc.E05-01-0007

  • H. Jiang

Structure of a thrombospondin C-terminal fragment reveals a novel calcium core in the type 3 repeats. 

EMBO J  . 2004 Mar 11 ; 23(6) 1223 | DOI : 10.1038/sj.emboj.7600166

  • M. Kvansakul

Positively charged residues at the five-fold symmetry axis of cell culture-adapted foot-and-mouth disease virus permit novel receptor interactions.

J Virol. . 2013 Jun 05 ; 87(15) 8735 | DOI : 10.1128/JVI.01138-13

  • S. Berryman

Functional integrin subunits regulating cell–matrix interactions in the intervertebral disc.

J Orthopaedic Res . 2007 Jun 01 ; 25(6) 829 | DOI : 10.1002/jor.20343

  • C. Gilchrist

Cell–Matrix Entanglement and Mechanical Anchorage of Fibroblasts in Three-dimensional Collagen Matrices

Mol Biol Cell . 2005 Nov 01 ; 16(11) 5070 | DOI : 10.1091/mbc.E05-01-0007

  • J. Huang
  • F. Grinnell

Occurrence of oligosialic acids on Integrin α5 subunit and their involvement in cell adhesion to fibronectin.

J Biol Chem . 2001 Jun 19 ; 276(36) 33657 | DOI : 10.1074/jbc.M011100200

  • S. Nadanaka

References

A Novel Disintegrin Salmosin Inhibits Tumor Angiogenesis

Cancer Res. . 1999 Aug 01 ; 59 3754 | DOI : PMID: 10446992

  • I-C. Kang
  • et al