Peptides  >  Cell Permeable Peptides (CPP) / Drug Delivery Peptides  >>  Transportan

This peptide is Transportan (TP), a 27 amino acids (aa) long chimeric peptide containing 12 aa from the amino-terminal part of the neuropeptide galanin and the 14 aa long mastoparan (Vespula lewisii wasp venom), connected via a lysine residue. TP reveals some characteristic features of both galanin and mastoparan since it inhibits the binding of galanin to GALR-1 receptor as well as modulates the activity of G proteins due to the inhibition of GTPase activity.