Glucagon (1-29), bovine, human, rat, porcine, Biotin-labeled
- Cat.Number : AS-60274-05
- Manufacturer Ref. :
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In production
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This is N-terminal biotin labeled Glucagon (1-29). Glucagon is a peptide hormone secreted from the pancreatic Islet of Langerhans alpha-cells, in response to low circulating blood glucose levels in order to restore normal glucose levels. It acts on hepatic enzymes that regulate glucose production and glycogen synthesis. Excessive amounts of circulating glucagon levels is implicated in the metabolic dysregulation of type 2 diabetes, since such conditions result in hyperglycaemia.
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Citations
A novel high-sensitivity electrochemiluminescence (ECL) sandwich immunoassay for the specific quantitative measurement of plasma glucagon.
Clin Biochem . 2012 Aug 04 ; 45(18) 1640 | DOI : 10.1016/j.clinbiochem.2012.07.111.
- JH. Sloan
References
Characterisation of structurally modified analogues of glucagon as potential glucagon receptor antagonists
Mol Cell Endocrinol . 2013 Dec 05 ; 381(1-2) 26 | DOI : 10.1016/j.mce.2013.07.014
- FP. O'Harte
- et al