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Peptides  >  HIV Related Peptides  >>  Cys(Npys)-TAT (47-57), FAM-labeled

Product Name Cys(Npys) - TAT (47 - 57), FAM - labeled
C(Npys)YGRKKRRQRRR - K(FAM) - NH2
Size 1 mg
Catalog # AS-61213
US$ $291
Description

This peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This is synthesized with C(Npys) at the N-terminus for applications requiring specific conjugation reactions and has a fluorophore labeled with FAM having Abs/Em=494/518 nm. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.

Detailed Information Material Safety Data Sheets (MSDS)
Storage -20C
References 1, Bright R. et al. Neurosci lett. 441, 120-124 (2008)
2, Moultin HM. Et al. Bioconj Chem. 15(2):290-299 (2004).
Molecular Weight 2302.7
Sequence
(One-Letter Code)
C(Npys)YGRKKRRQRRR-K(FAM)-NH2
Sequence
(Three-Letter Code)
Cys(Npys) - Tyr - Gly - Arg - Lys - Lys - Arg - Arg - Gln - Arg - Arg - Arg - Lys(FAM) - NH2
     
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