AMC (7-amino-4-methylcoumarin)-derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AMC peptides by caspases generates strongly fluorescent AMC that is monitored fluorimetrically at 440-460 nm with excitation of 340-350 nm.
Caspase-1 substrate with Km/Kcat = 3.3×106 M-1s-1
-20°C desiccated and protected from light
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