IMG-EN-AS-61620-01.jpg
Peptides

MOG (44-54), mouse, human, rat - 1 mg

$110.00
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  • Cat.Number : AS-61620
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This 11mer peptide derived from myelin oligodendrocyte glycoprotein (MOG) (amino acids 44–54; conserved in human, mouse, rat) represents the core binding epitope for MOG-specific CD8+ T cells. This is the minimal, functionally constant, length of the MOG (35–55) peptide that binds to CD8+ MOG-specific T cells and stimulates T cell proliferation in vitro.

Specifications

Chemistry
Sequence one letter code
  • FSRVVHLYRNG
Sequence three letter code
  • H-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-OH
Molecular Formula
  • C61H94N20O15
Molecular Mass/ Weight
  • 1347.6
Modification
Conjugation
  • Unconjugated
Quantity & Purity
Purity
  • Peak Area by HPLC ≥95%
Storage & stability
Form
  • Lyophilized
Storage Conditions
  • - 20 °C
Activity
Biomarker Target
Research Area
Sub-category Research Area
Usage
  • Research use
Source
Source / Species
  • Human, mouse, rat

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References

Myelin oligodendrocyte glycoprotein peptide-induced experimental allergic encephalomyelitis and T cell responses are unaffected by immunoproteasome deficiency

J Neuroimmunol  . 2007 Oct 26 ; 192(1-2) 124 | DOI : 10.1016/j.jneuroim.2007.09.024

  • RF. Frausto

Encephalitogenic activity of truncated myelin oligodendrocyte glycoprotein (MOG) peptides and their recognition by CD8+ MOG‐specific T cells on oligomeric MHC class I molecules

Int Immunol . 2003 Jan 01 ; 15(2) 261 | DOI : https://doi.org/10.1093/intimm/dxg023

  • D. Sun
  • et al